Mycobacterium avium strain RCAD0278

Gram-negativeRodMotileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium avium strain RCAD0278 is a heterotrophic, aerobic, gram-negative bacterium characterized by its rod shape and ability to move, facilitated by the presence of flagella. This strain has a single replicon and is surrounded by two membranes, a feature typical of its genus. It thrives optimally at 37°C, categorizing it as mesophilic, with the capacity to inhabit multiple environments. M. avium strain RCAD0278 is noted for its free-living biotic relationship and has been identified in various hosts, including Homo sapiens (humans), Bos taurus (cattle), Sus scrofa (pigs), Capra hircus (goats), as well as other Metazoa and Mammalia species. The health effects associated with this strain are significant, as it can cause a variety of pulmonary diseases, including tuberculosis, chronic pulmonary infections, and localized lesions. It is also associated with opportunistic infections in immunocompromised individuals, leading to conditions such as NTM lung disease and hypersensitivity-like lung disease. The presence of M. avium strain RCAD0278 in diverse hosts suggests its ecological versatility and adaptability, which may contribute to its role in pulmonary diseases across different species, including humans. This highlights the importance of monitoring and understanding such pathogens in both human health and veterinary contexts, given their potential for causing serious health issues.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium avium
Strainstrain RCAD0278

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Mycobacterium avium strain RCAD0278
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementSingles
SporulationNot Available
Energy sourceHeterotroph
PathogenicityNot Available

Genome Summary

Mycobacterium avium strain RCAD0278


Gene Summary

Adenine Count

760977 bp

Thymine Count

760067 bp

Guanine Count

1714865 bp

Cytosine Count

1717701 bp

Genome Length

4953610 bp

Protein-coding Genes

4591 genes

Non-Coding Genes

62 genes

# of Chromosomes/Plasmids

1

Genes

No genes available for this genome.

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

466 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000198tetracenomycin CC23H20O11Chemical structure of tetracenomycin CNot available
Average472.402Da
Monoisotopic472.100561464Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da

Displaying 1–10 of 466 metabolites

Health Effects

Health ConditionRelationReference
NecrosisCausesPMC11064574
Lung infectionsCausesPMC11807137
TuberculosisCausesPMC12017052
Chronic pulmonary and disseminated infectionsCausesPMC12871676
Hypersensitivity-like lung diseaseCausesPMC4589115
Hot tub lungCausesPMC4589115
SpnCausesPMC8272905
PleuritisCausesPMC8272905
Pulmonary diseaseCausesPMC12822083
Pulmonary infectionCausesPMC12822083

Displaying health effects 1 – 10 of 17 in total