Escherichia coli strain MS6198

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain MS6198 is a pathogenic, Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. It exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. This strain has an optimal growth temperature of 37°C and falls within the mesophilic temperature range, making it well-suited for growth in warm-blooded hosts. E. coli MS6198 is host-associated, living freely in diverse environments, and is known to inhabit multiple hosts, including humans (Homo sapiens), domestic animals (e.g., Gallus gallus, Bos taurus, Sus scrofa), and various other vertebrates and invertebrates. The bacterium has significant health implications, being associated with a wide range of clinical conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and even severe complications like hemolytic uremic syndrome (HUS). The strain is equipped with five replicons and contains two membranes, which may contribute to its adaptability and survival in different hosts. The extensive list of hosts indicates its ecological versatility, highlighting its role in various biological systems. The presence of E. coli MS6198 in such a wide range of organisms emphasizes its importance in both health and disease, suggesting that interventions targeting this strain could have broad implications for public health and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain MS6198

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain MS6198
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain MS6198


Gene Summary

Adenine Count

33965 bp

Thymine Count

34089 bp

Guanine Count

33144 bp

Cytosine Count

35129 bp

Genome Length

136327 bp

Protein-coding Genes

144 genes

Non-Coding Genes

17 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinMS6198_RS32160Not AvailablePositive834 - 9926104.21
helix-turn-helix transcriptional regulatorMS6198_RS27750Not AvailablePositive1030 - 131710825.4
hypothetical proteinMS6198_RS27755Not AvailablePositive1759 - 206412111.5
is1-like element is1b family transposaseMS6198_RS27760Not AvailableNegative2078 - 277526558.3
hypothetical proteinMS6198_RS27765Not AvailableNegative2831 - 398844561.7
hypothetical proteinMS6198_RS31385Not AvailableNegative4141 - 451514534.6
hok/gef family proteinMS6198_RS27775Not AvailablePositive4836 - 49885761.48
hypothetical proteinMS6198_RS27780Not AvailableNegative5060 - 53119297.11
dinq-like type i toxin dqlbMS6198_RS32265Not AvailablePositive5812 - 59073385.48
hypothetical proteinMS6198_RS31625Not AvailableNegative5972 - 61486907.3

Displaying genes 1 – 10 of 5541 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total