Escherichia coli strain C5

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain C5 is a Gram-negative, rod-shaped bacterium that exists in pairs or singles and is characterized as a facultative anaerobe. It thrives optimally at 37°C and falls within the mesophilic temperature range, indicating its preference for moderate temperatures. This strain possesses flagella, allowing for mobility, and has a complex cellular structure with two membranes and two replicons. E. coli C5 is primarily host-associated, showing a diverse range of hosts that includes Homo sapiens, various domesticated animals such as Gallus gallus (chickens), Bos taurus (cattle), Sus scrofa (pigs), and various species across the animal kingdom, including vertebrates and invertebrates like Acanthamoeba castellanii. Its biotic relationship is classified as free-living, indicating its adaptability to various environments and hosts. Importantly, E. coli C5 is linked to numerous health effects, particularly in humans, where it has been associated with urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and foodborne illnesses, among others. The strain's pathogenicity highlights its role in significant health challenges, including hemolytic uremic syndrome (HUS) and various forms of diarrhea, which can lead to severe complications such as renal failure and sepsis. This strain’s ability to infect a wide range of hosts and its association with serious health conditions underscores its ecological role in both environmental and clinical settings. The presence of E. coli C5 in diverse habitats and its potential for pathogenicity exemplify the complexities of microbial interactions within ecosystems and the importance of monitoring its impact on health and disease.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain C5

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain C5
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain C5


Gene Summary

Adenine Count

56266 bp

Thymine Count

55759 bp

Guanine Count

47863 bp

Cytosine Count

54557 bp

Genome Length

214445 bp

Protein-coding Genes

239 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
helix-turn-helix domain-containing proteinRG28_RS30890Not AvailableNegative10061 - 103069594.72
hypothetical proteinRG28_RS31550Not AvailableNegative10354 - 1079416732.3
yfdx family proteinRG28_RS28305Not AvailablePositive11328 - 1194522845.5
duf6862 domain-containing proteinRG28_RS28310Not AvailablePositive12220 - 1249810092.6
is110 family transposaseRG28_RS28315Not AvailableNegative12766 - 1377037161.4
duf6862 domain-containing proteinRG28_RS28320Not AvailablePositive13819 - 1466930432.1
hypothetical proteinRG28_RS31555Not AvailablePositive15216 - 1561114251.0
duf6862 domain-containing proteinRG28_RS32595Not AvailablePositive15624 - 157554699.93
mipa/ompv family proteinRG28_RS28330Not AvailableNegative16040 - 1678628033.7
duf6862 domain-containing proteinRG28_RS31560Not AvailablePositive17295 - 1781019484.8

Displaying genes 11 – 20 of 353 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total