Escherichia coli BW25113 strain K-12

Escherichia coli BW25113 strain K-12 is a gram-negative, rod-shaped bacterium that is facultatively anaerobic, thriving optimally at 37°C within a mesophilic temperature range. This strain possesses flagella, enabling mobility, and typically exists in pairs or singles in its habitat, which is predominantly host-associated. E. coli BW25113 is a free-living organism with a diverse range of hosts, including various mammals (e.g., Homo sapiens, Bos taurus, Canis lupus familiaris), birds (e.g., Gallus gallus, Meleagris gallopavo), and even plants (e.g., Solanum lycopersicum, Brassica oleracea var. italica). This adaptability allows it to colonize numerous environments, making it a significant organism in both ecological and clinical contexts. The strain is associated with a variety of health effects, particularly in humans, where it is linked to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. Other health implications include diarrhea, septicemia, and hemolytic uremic syndrome (HUS). These pathogenic traits underscore its relevance in clinical microbiology and public health. The extensive range of hosts and health effects associated with E. coli BW25113 strain K-12 illustrates its ecological versatility and the potential for cross-species transmission of pathogenic strains. Understanding its interactions with various hosts can provide insights into the dynamics of microbial pathogenesis and the importance of monitoring E. coli in both human health and environmental contexts.