Escherichia coli BW25113 strain K-12

Escherichia coli BW25113 strain K-12 is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as single cells. This strain is notably adapted to a host-associated habitat, reflecting its common presence in the intestines of warm-blooded organisms. E. coli BW25113 K-12 is a facultative anaerobe, indicating its ability to grow in both the presence and absence of oxygen, which contributes to its versatility in various environments. The optimal growth temperature for this strain is around 37.0°C, aligning with the typical body temperature of its host organisms, further emphasizing its adaptation to a host-associated lifestyle. This strain serves as a model organism in molecular biology and genetic studies due to its well-characterized genome and the ease with which it can be manipulated in laboratory settings. The ecological significance of E. coli BW25113 K-12 extends beyond its role as a gut inhabitant; it is involved in nutrient cycling and can impact the microbiome composition of its host. Understanding the traits of this strain can offer insights into the dynamics of microbial communities in host-associated habitats and the potential implications for health and disease.