Escherichia coli strain E2855

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain E2855 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, allowing it to thrive in both aerobic and anaerobic environments. This strain is mobile due to the presence of flagella and typically exists in pairs or singles. The optimal growth temperature for E2855 is 37°C, classifying it as mesophilic. E2855 is host-associated and free-living, with a broad range of hosts, including Homo sapiens (humans), various livestock such as Bos taurus (cattle) and Gallus gallus (chickens), as well as numerous other vertebrates and invertebrates. Notably, it has been identified in association with plants such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli), indicating a potential ecological role in plant-associated microbiomes. This strain is linked to a multitude of health effects, primarily in humans, where it is known to cause urinary tract infections, gastrointestinal infections, and other serious conditions such as neonatal meningitis and hemolytic uremic syndrome. The pathogenicity of E2855 highlights its significance in clinical microbiology, particularly concerning foodborne illnesses and urinary tract infections. The diversity of hosts and the extensive health implications associated with E2855 underscore the complex interactions between this E. coli strain and both human health and environmental ecosystems. This diversity may reflect evolutionary adaptations that enable it to thrive in varying habitats, including both animal and plant hosts, thereby influencing disease dynamics and ecological balances.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain E2855

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain E2855
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain E2855 plasmid pE2855-2, complete sequence.

Gene Summary

Adenine Count

25016 bp

Thymine Count

25254 bp

Guanine Count

22157 bp

Cytosine Count

22019 bp

Genome Length

94446 bp

Protein-coding Genes

7 genes

Non-Coding Genes

105 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
incfii family plasmid replication initiator repaMCREHEC_RS30730Not AvailablePositive1 - 85832647.6
plasmid stabilization proteinMCREHEC_RS30750Not AvailablePositive1864 - 21279958.67
type ii toxin-antitoxin system rele/pare family toxinMCREHEC_RS30755Not AvailablePositive2117 - 241611545.6
yada-like family proteinMCREHEC_RS30760Not AvailablePositive2427 - 26579271.81
helicase c-terminal domain-containing proteinMCREHEC_RS30765Not AvailableNegative3128 - 486465610.8
is91 family transposaseMCREHEC_RS30770Not AvailableNegative5205 - 639246346.5
hypothetical proteinMCREHEC_RS30775Not AvailableNegative6392 - 675713761.2
dead/deah box helicaseMCREHEC_RS30780Not AvailableNegative6792 - 755628650.1
hypothetical proteinMCREHEC_RS30785Not AvailableNegative7669 - 856233822.5
yada-like family proteinMCREHEC_RS30790Not AvailableNegative9302 - 965813438.4

Displaying genes 1 – 10 of 209 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total