Neisseria meningitidis strain INS-Nm1124

Neisseria meningitidis strain INS-Nm1124 is a Gram-negative, cocci-shaped bacterium that typically exists in pairs and is classified as an aerobe, indicating its requirement for oxygen for growth. This strain is mesophilic, with an optimal growth temperature of 35°C, and it is characterized by the presence of two membranes and a single replicon. Despite possessing flagella, N. meningitidis INS-Nm1124 is non-motile. As a host-associated organism, N. meningitidis primarily resides in Homo sapiens and is known for its pathogenic potential. It is associated with several serious health conditions, including meningitis, sepsis, cellulitis, septicemia, and severe sepsis. The strain is implicated in invasive meningococcal disease (IMD), which encompasses meningococcal meningitis and meningococcal septicemia, both of which can lead to acute bacterial meningitis (ABM). The free-living biotic relationship of this strain reflects its capacity to thrive in specific host environments, yet its pathogenicity underscores the potential public health risks it poses. Understanding the ecological niche and pathogenic mechanisms of Neisseria meningitidis is crucial for developing preventive measures and treatment strategies against its associated diseases. The accessions for strain INS-Nm1124 are cataloged as NWXB00000000.1, which serves as a reference for researchers studying this organism.