Finegoldia magna strain 12T272 21c

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Tissierellia

Order

Tissierellales

Family

Peptoniphilaceae

Genus

Finegoldia

Description

Finegoldia magna strain 12T272 21c is a Gram-positive, anaerobic coccus that exhibits a free-living biotic relationship. This strain is mesophilic, thriving within a temperature range conducive to human health environments. Notably, it lacks mobility and does not possess flagella, indicating a non-motile lifestyle. F. magna is significant in clinical microbiology, as it has been associated with various human infections, including endocarditis, prosthetic joint infections, necrotizing pneumonia, necrotising fasciitis, and emphysematous pyelonephritis (EPN). Its ability to cause such a range of infections highlights the pathogenic potential of this anaerobe in immunocompromised or vulnerable populations. The strain contains a single replicon and a single membrane, which is characteristic of many anaerobic bacteria. Its presence in multiple habitats suggests adaptability and potential for survival in diverse environments, although its primary host is Homo sapiens. Understanding the ecological role of Finegoldia magna, particularly in human health contexts, underscores the importance of monitoring its presence in clinical settings, especially given its association with serious infections. Enhanced awareness of pathogenic bacteria such as F. magna can aid in the development of targeted medical interventions and treatments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassTissierellia
OrderTissierellales
FamilyPeptoniphilaceae
GenusFinegoldia
SpeciesFinegoldia magna
Strainstrain 12T272 21c

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Finegoldia magna strain 12T272 21c
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Finegoldia magna strain 12T272 21c


Gene Summary

Adenine Count

619623 bp

Thymine Count

654937 bp

Guanine Count

283740 bp

Cytosine Count

313957 bp

Genome Length

1872257 bp

Protein-coding Genes

1698 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter substrate-binding proteinB9N53_00395Not AvailablePositive73295 - 7424834950.0
phosphate abc transporter permease subunit pstcB9N53_00400Not AvailablePositive74311 - 7517732615.8
phosphate abc transporter permeaseB9N53_00405Not AvailablePositive75164 - 7601531234.9
phosphate abc transporter atp-binding proteinB9N53_00410Not AvailablePositive75993 - 7667025735.0
dna-binding response regulatorB9N53_00415Not AvailablePositive76697 - 7739827406.2
two-component sensor histidine kinaseB9N53_00420Not AvailablePositive77391 - 7847342215.9
lactococcin 972 family bacteriocinB9N53_00425Not AvailablePositive78725 - 7911114386.7
hypothetical proteinB9N53_00430Not AvailablePositive79198 - 8135783457.5
bacteriocin abc transporter atp-binding proteinB9N53_00435Not AvailablePositive81358 - 8204125887.7
capsular biosynthesis proteinB9N53_00440Not AvailablePositive82255 - 8339745160.5

Displaying genes 81 – 90 of 121 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infections in human beingsCausesPMC10127037
InfectionsCausesPMC10127037
EndocarditisCausesPMC10127037
Prosthetic joint infectionsCausesPMC10127037
Necrotizing pneumoniaCausesPMC10127037
Necrotising fasciitisCausesPMC7259851
Emphysematous pyelonephritisCausesPMC7480896
EpnCausesPMC7480896
Infectious diseasesCausesPMC2650633

Displaying health effects 1 – 9 of 9 in total