Helicobacter pylori UM037

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori UM037 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spiral shape, classified as spirilla. This organism is typically found in a host-associated habitat, indicating that it resides within a living host. Notably, H. pylori UM037 exhibits a single cell arrangement, and it possesses flagella, which may play a role in its motility, although the strain is categorized as non-motile in the context of its ecological interactions. The optimal growth temperature for H. pylori UM037 is 37°C, placing it within the mesophilic temperature range. This temperature preference aligns with its habitat, as it typically inhabits the human gastric environment, which maintains a similar temperature. The bacterium has a unique cellular structure featuring two membranes and a single replicon, which is characteristic of its phylogenetic group. In terms of its biotic relationship, H. pylori UM037 is noted to be free-living, which suggests that it can exist independently within its host environment, possibly contributing to its adaptability and survival. The strain is cataloged under accession NC_021217.3, providing a reference for genetic and genomic studies. The presence of H. pylori in the gastric environment has significant implications for human health, as this bacterium is associated with various gastrointestinal diseases, including gastritis and peptic ulcers. Understanding its biological traits aids in comprehending its role in host-pathogen interactions and the ecological dynamics within the gastrointestinal microbiome.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainUM037

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori UM037
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori UM037


Gene Summary

Adenine Count

516999 bp

Thymine Count

517414 bp

Guanine Count

323316 bp

Cytosine Count

335065 bp

Genome Length

1692794 bp

Protein-coding Genes

1567 genes

Non-Coding Genes

78 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gp26K750_RS01895Not AvailableNegative384573 - 38527727537.5
hd domain-containing proteinK750_RS01900Not AvailableNegative385277 - 38649747318.2
Hypothetical proteinK750_RS01905Not AvailablePositive386919 - 3871799549.1
AttlNot AvailableNot AvailablePositive386961 - 386974Not Available
Putative integraseK750_RS01910Not AvailablePositive387179 - 38830043107.7
Hypothetical proteinK750_RS01915Not AvailablePositive388297 - 3885158531.34
hypothetical proteinK750_RS08670Not AvailablePositive388517 - 3886846230.01
Hypothetical proteinK750_RS01920Not AvailablePositive388686 - 38961836301.8
Hypothetical proteinK750_RS01925Not AvailablePositive389636 - 38999214428.8
Putative dna helicase, putative dna repair proteinK750_RS01930Not AvailablePositive390102 - 39128045580.8

Displaying genes 1 – 10 of 1645 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

21 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00019773,4-dihydroxybenzoateC7H5O4Chemical structure of 3,4-dihydroxybenzoateNot available
Average153.114Da
Monoisotopic153.019332221Da
BASm0002759dTDP-beta-L-rhamnoseC16H24N2O15P2Not availableNot available
Average546.316Da
Monoisotopic546.066289237Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm00030222-methyl-cis-aconitateC7H5O6Chemical structure of 2-methyl-cis-aconitateNot available
Average185.113Da
Monoisotopic185.0102586Da
BASm0003334aldehydo-D-ribose 5-phosphateC5H11O8PChemical structure of aldehydo-D-ribose 5-phosphateNot available
Average230.1098Da
Monoisotopic230.0191538Da

Displaying 1–10 of 21 metabolites

Health Effects

No health effects information available for this bacterium.