Bacteroides fragilis 638R

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis 638R is a gram-negative, rod-shaped bacterium that is classified as a chemoorganotroph, utilizing organic compounds as its energy source. This species is characterized by its anaerobic lifestyle, thriving in environments devoid of oxygen. B. fragilis 638R is typically found in host-associated habitats, indicating a close relationship with its host organisms, which include humans and other animals. The bacterium is non-motile and does not possess flagella, which suggests that it relies on other means for spatial distribution within its ecological niche. B. fragilis 638R exists as single cells rather than forming clusters or chains, which may influence its interactions with other microorganisms in the gastrointestinal tract. Optimal growth of B. fragilis 638R occurs at a temperature of 37°C, aligning with the typical body temperature of its host, and it is classified as mesophilic, indicating a preference for moderate temperature ranges. The organism possesses a complex cell structure, characterized by two membranes, which is a common trait among gram-negative bacteria. It contains one replicon, which simplifies its genetic maintenance. Ecologically, B. fragilis 638R plays a significant role in the gut microbiome, contributing to the breakdown of complex carbohydrates and the production of short-chain fatty acids, which are beneficial for host health. Its free-living nature, coupled with its adaptation to anaerobic conditions, underscores its importance in maintaining the balance of gut microbiota and supporting overall digestive health.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strain638R

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis 638R
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Bacteroides fragilis 638R, complete sequence.

Gene Summary

Adenine Count

1516915 bp

Thymine Count

1523463 bp

Guanine Count

1164365 bp

Cytosine Count

1168378 bp

Genome Length

5373121 bp

Protein-coding Genes

4308 genes

Non-Coding Genes

109 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidinol dehydrogenaseBF638R_RS14510Not AvailableNegative3553433 - 355471946578.2
atp phosphoribosyltransferaseBF638R_RS14515Not AvailableNegative3554755 - 355560631237.4
paai family thioesteraseBF638R_RS14520Not AvailableNegative3555854 - 355634518990.8
pirin family proteinBF638R_RS14525Not AvailablePositive3556467 - 355717426921.0
protein-disulfide reductase dsbd family proteinBF638R_RS14530Not AvailableNegative3557260 - 355926973882.9
dabb family proteinBF638R_RS14535Not AvailableNegative3559370 - 355966911280.6
uridine kinaseBF638R_RS14540Not AvailablePositive3559771 - 356038523195.4
transglycosylase slt domain-containing proteinBF638R_RS14545Not AvailablePositive3560382 - 356177352361.8
sodium:solute symporterBF638R_RS14550Not AvailableNegative3561833 - 356338656444.9
symporter small accessory proteinBF638R_RS25615Not AvailableNegative3563383 - 35635084830.9

Displaying genes 2951 – 2960 of 4417 in total

Metabolites

429 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da

Displaying 1–10 of 429 metabolites

Health Effects

No health effects information available for this bacterium.