Gardnerella vaginalis ATCC 14019

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis ATCC 14019 is a Gram-positive, rod-shaped bacterium that is classified as a chemoheterotroph, deriving its energy from organic compounds. This organism thrives in anaerobic conditions, making it well-suited for its habitat in the human host, particularly within the vaginal microbiome. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, indicative of its adaptation to human body temperature. G. vaginalis is non-motile and does not possess flagella, which suggests that it relies on other mechanisms for its dispersal within the host environment. It contains a single membrane and one replicon, indicating a relatively simple cellular structure that aligns with its free-living biotic relationship. The pathogenicity of G. vaginalis is notable, as it is associated with bacterial vaginosis, a condition that can lead to various reproductive health issues. Despite being a part of the normal vaginal flora in some individuals, its overgrowth can disrupt the ecological balance, leading to adverse health effects. Understanding the ecological role of G. vaginalis is essential, as it highlights the complex interactions within the vaginal microbiome. Its capacity to thrive in anaerobic conditions while causing pathogenic effects under certain circumstances illustrates the delicate balance that exists between beneficial and harmful microorganisms in host-associated habitats. The accession number for further genomic insights is NC_014644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainATCC 14019

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis ATCC 14019
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityYes

Genome Summary

Gardnerella vaginalis ATCC 14019


Gene Summary

Adenine Count

488860 bp

Thymine Count

488822 bp

Guanine Count

347339 bp

Cytosine Count

342329 bp

Genome Length

1667350 bp

Protein-coding Genes

1272 genes

Non-Coding Genes

54 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinHMPREF0421_RS00005Not AvailableNegative67 - 79824602.4
f0f1 atp synthase subunit epsilonHMPREF0421_RS00010Not AvailableNegative1420 - 173411168.5
f0f1 atp synthase subunit betaHMPREF0421_RS00015Not AvailableNegative1737 - 322453918.7
f0f1 atp synthase subunit gammaHMPREF0421_RS00020Not AvailableNegative3231 - 423536613.1
f0f1 atp synthase subunit alphaHMPREF0421_RS00025Not AvailableNegative4239 - 590059944.7
fof1 atp synthase subunit deltaHMPREF0421_RS00030Not AvailableNegative5918 - 649921334.4
f0f1 atp synthase subunit bHMPREF0421_RS00035Not AvailableNegative6575 - 711719693.4
atp synthase f0 subunit cHMPREF0421_RS00040Not AvailableNegative7178 - 74118007.19
f0f1 atp synthase subunit aHMPREF0421_RS00045Not AvailableNegative7502 - 836231551.9
Trna-metNot AvailableNot AvailablePositive8743 - 8816Not Available

Displaying genes 1 – 10 of 1326 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.