Gardnerella vaginalis ATCC 14019

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis ATCC 14019 is a Gram-positive, rod-shaped bacterium that is classified as a chemoheterotroph, deriving its energy from organic compounds. This organism thrives in anaerobic conditions, making it well-suited for its habitat in the human host, particularly within the vaginal microbiome. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, indicative of its adaptation to human body temperature. G. vaginalis is non-motile and does not possess flagella, which suggests that it relies on other mechanisms for its dispersal within the host environment. It contains a single membrane and one replicon, indicating a relatively simple cellular structure that aligns with its free-living biotic relationship. The pathogenicity of G. vaginalis is notable, as it is associated with bacterial vaginosis, a condition that can lead to various reproductive health issues. Despite being a part of the normal vaginal flora in some individuals, its overgrowth can disrupt the ecological balance, leading to adverse health effects. Understanding the ecological role of G. vaginalis is essential, as it highlights the complex interactions within the vaginal microbiome. Its capacity to thrive in anaerobic conditions while causing pathogenic effects under certain circumstances illustrates the delicate balance that exists between beneficial and harmful microorganisms in host-associated habitats. The accession number for further genomic insights is NC_014644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainATCC 14019

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis ATCC 14019
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityYes

Genome Summary

Gardnerella vaginalis ATCC 14019


Gene Summary

Adenine Count

488860 bp

Thymine Count

488822 bp

Guanine Count

347339 bp

Cytosine Count

342329 bp

Genome Length

1667350 bp

Protein-coding Genes

1272 genes

Non-Coding Genes

54 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamyl-q trna(asp) synthetaseHMPREF0421_RS00405Not AvailableNegative81184 - 8223338400.8
mip/aquaporin family proteinHMPREF0421_RS00410Not AvailableNegative82396 - 8312725969.2
rna degradosome polyphosphate kinaseHMPREF0421_RS00415Not AvailablePositive83693 - 8593084098.8
atp-binding proteinHMPREF0421_RS00420Not AvailableNegative86020 - 8738752720.3
aaa family atpaseHMPREF0421_RS00425Not AvailablePositive87757 - 8908249816.6
rlob family proteinHMPREF0421_RS00430Not AvailablePositive89138 - 8986027524.8
nudix hydrolaseHMPREF0421_RS00435Not AvailablePositive90164 - 9132743501.7
hypothetical proteinHMPREF0421_RS00440Not AvailablePositive91374 - 9203623989.6
uracil phosphoribosyltransferaseHMPREF0421_RS00445Not AvailablePositive92334 - 9297223490.6
type 1 glutamine amidotransferaseHMPREF0421_RS00450Not AvailableNegative93083 - 9388929789.2

Displaying genes 81 – 90 of 1326 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.