Gardnerella vaginalis ATCC 14019

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis ATCC 14019 is a Gram-positive, rod-shaped bacterium that is classified as a chemoheterotroph, deriving its energy from organic compounds. This organism thrives in anaerobic conditions, making it well-suited for its habitat in the human host, particularly within the vaginal microbiome. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, indicative of its adaptation to human body temperature. G. vaginalis is non-motile and does not possess flagella, which suggests that it relies on other mechanisms for its dispersal within the host environment. It contains a single membrane and one replicon, indicating a relatively simple cellular structure that aligns with its free-living biotic relationship. The pathogenicity of G. vaginalis is notable, as it is associated with bacterial vaginosis, a condition that can lead to various reproductive health issues. Despite being a part of the normal vaginal flora in some individuals, its overgrowth can disrupt the ecological balance, leading to adverse health effects. Understanding the ecological role of G. vaginalis is essential, as it highlights the complex interactions within the vaginal microbiome. Its capacity to thrive in anaerobic conditions while causing pathogenic effects under certain circumstances illustrates the delicate balance that exists between beneficial and harmful microorganisms in host-associated habitats. The accession number for further genomic insights is NC_014644.1.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainATCC 14019

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis ATCC 14019
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityYes

Genome Summary

Gardnerella vaginalis ATCC 14019, complete sequence.

Gene Summary

Adenine Count

488860 bp

Thymine Count

488822 bp

Guanine Count

347339 bp

Cytosine Count

342329 bp

Genome Length

1667350 bp

Protein-coding Genes

1272 genes

Non-Coding Genes

54 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidine--trna ligaseHMPREF0421_RS04060Not AvailableNegative1014657 - 101605751226.4
duf349 domain-containing proteinHMPREF0421_RS04065Not AvailablePositive1016154 - 101752151752.6
mrp/nbp35 family atp-binding proteinHMPREF0421_RS04070Not AvailableNegative1017585 - 101873341081.8
nad-dependent dna ligase ligaHMPREF0421_RS04075Not AvailableNegative1018743 - 1021625106739.0
tetratricopeptide repeat proteinHMPREF0421_RS04080Not AvailableNegative1021712 - 1025011124013.0
lysr substrate-binding domain-containing proteinHMPREF0421_RS04085Not AvailableNegative1025282 - 102618133589.1
alkyl hydroperoxide reductase subunit fHMPREF0421_RS04090Not AvailableNegative1026271 - 102788457044.8
alkyl hydroperoxide reductase subunit cHMPREF0421_RS04095Not AvailableNegative1027960 - 102852320785.5
Trna-glyNot AvailableNot AvailablePositive1028795 - 1028870Not Available
alcohol dehydrogenase adhpHMPREF0421_RS04105Not AvailablePositive1029176 - 103018635651.1

Displaying genes 811 – 820 of 1326 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.