Streptococcus pyogenes MGAS10750

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes MGAS10750 is a Gram-positive cocci bacterium that typically arranges itself in chains or pairs. As a facultative anaerobe, it can thrive in both the presence and absence of oxygen, making it adaptable to various environments. This strain is classified as mesophilic, with an optimal growth temperature of 30°C, which aligns with the temperature ranges commonly found in host organisms. Notably, Streptococcus pyogenes MGAS10750 is recognized for its pathogenicity, meaning it has the potential to cause disease in its host. It is nonsporulating and possesses a single membrane, indicating a simpler cellular structure compared to more complex organisms. The bacterium does not exhibit mobility, as it lacks flagella, which may influence its method of colonization and infection. In terms of its ecological role, Streptococcus pyogenes MGAS10750 is described as free-living but is primarily host-associated, indicating a significant relationship with its host organisms. This dual nature of being free-living while also having the capability to cause diseases in hosts highlights its ecological adaptability and the potential impact on host health. The accession number NC_008024.1 identifies the genomic sequence of this strain, which can be crucial for further studies on its genetics and pathogenic mechanisms. Understanding the characteristics of Streptococcus pyogenes MGAS10750 contributes to broader insights into microbial pathogenesis and the importance of host-associated bacteria in health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
StrainMGAS10750

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes MGAS10750
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementChains - Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Streptococcus pyogenes MGAS10750


Gene Summary

Adenine Count

601278 bp

Thymine Count

593611 bp

Guanine Count

376164 bp

Cytosine Count

366058 bp

Genome Length

1937111 bp

Protein-coding Genes

1663 genes

Non-Coding Genes

285 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AtpaseMGAS10750_RS02820Not AvailablePositive543062 - 54395233589.1
yvck family proteinMGAS10750_RS02825Not AvailablePositive543949 - 54492635739.1
dna-binding protein whiaMGAS10750_RS02830Not AvailablePositive544923 - 54583433902.8
AttlNot AvailableNot AvailablePositive545989 - 546009Not Available
Putative integraseMGAS10750_RS02835Not AvailableNegative546031 - 54744654721.8
Orf2MGAS10750_RS02840Not AvailableNegative547597 - 54813920090.5
Putative ci repressorMGAS10750_RS02845Not AvailableNegative548165 - 54891428109.1
Putative transmembrane proteinMGAS10750_RS09865Not AvailablePositive549301 - 5494595969.38
hypothetical proteinMGAS10750_RS02850Not AvailableNegative549558 - 55019924484.5
RepressorMGAS10750_RS02855Not AvailablePositive550292 - 5504987533.27

Displaying genes 1 – 10 of 1948 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

95 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da

Displaying 1–10 of 95 metabolites

Health Effects

No health effects information available for this bacterium.