Neisseria meningitidis strain S00-1225

Neisseria meningitidis strain S00-1225 is a Gram-negative, aerobic cocci bacterium that typically exists in pairs. It is classified as mesophilic, with an optimal growth temperature of 35°C, and possesses no mobility due to the absence of flagella. The strain has a complex cellular structure, consisting of two membranes and a single replicon. This bacterium is host-associated, primarily inhabiting humans (Homo sapiens), and is known for its pathogenic potential. N. meningitidis strain S00-1225 is associated with a range of serious health conditions, including meningitis, sepsis, cellulitis, and septicemia. Specifically, it can lead to invasive meningococcal disease (IMD), which encompasses several severe manifestations, such as meningococcal meningitis and meningococcal septicemia. The variety of diseases linked to this strain highlights its significant impact on human health. Ecologically, N. meningitidis can be considered free-living in certain contexts, although it predominantly relies on human hosts for its survival and propagation. The ability to cause severe illness underscores the importance of understanding this pathogen, as it has implications for public health and disease prevention. Monitoring and studying strains like S00-1225 are critical for developing effective vaccines and treatment strategies against meningococcal disease. Accessions for this strain include MNMJ00000000.1, which can be referenced for further genomic analysis and research.