Escherichia coli strain STEC 1686

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain STEC 1686 is a pathogenic, Gram-negative bacterium characterized by its rod shape and facultative anaerobic metabolism. It is motile, possessing flagella, and typically arranges itself in pairs or as singles. With an optimal growth temperature of 37°C, it falls within the mesophilic temperature range. This strain has a unique biotic relationship as it is free-living, yet associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and numerous other vertebrates and invertebrates. STEC 1686 is implicated in a range of health issues, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The extensive list of health effects includes diarrhea, peritonitis, septicemia, food poisoning, and complications related to pregnancy, such as abortion and neonatal mortality. The strain's ability to cause diverse diseases highlights its pathogenic potential. The wide host range indicates that STEC 1686 may play a significant role in both ecological and health-related contexts, affecting various species and contributing to the transmission of pathogenic traits across different environments. This adaptability suggests that E. coli strains like STEC 1686 can influence microbial dynamics within their ecosystems and pose public health risks, emphasizing the need for ongoing surveillance and research to mitigate their impact.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain STEC 1686

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain STEC 1686
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain STEC 1686


Gene Summary

Adenine Count

1395711 bp

Thymine Count

1389689 bp

Guanine Count

1442638 bp

Cytosine Count

1415294 bp

Genome Length

5643434 bp

Protein-coding Genes

5033 genes

Non-Coding Genes

518 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive50711 - 50722Not Available
Putative integrase proteinAML35_00260Not AvailablePositive51068 - 5233048827.2
hypothetical proteinAML35_00265Not AvailablePositive52327 - 5297723672.8
hypothetical proteinAML35_00270Not AvailablePositive53364 - 535798202.87
Hypothetical proteinAML35_00275Not AvailablePositive53647 - 5436627006.5
Trna-leu;Not AvailableNot AvailablePositive54270 - 54356Not Available
Trna-cys;Not AvailableNot AvailablePositive54369 - 54442Not Available
Trna-gly;Not AvailableNot AvailablePositive54497 - 54572Not Available
hypothetical proteinAML35_00280Not AvailableNegative54634 - 548709365.46
hypothetical proteinAML35_00285Not AvailableNegative54928 - 551076559.87

Displaying genes 1 – 10 of 5551 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

90 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000433malonateC3H2O4Chemical structure of malonateNot available
Average102.0456Da
Monoisotopic101.9953086Da
BASm00006812-dehydro-D-glucoseC6H10O6Chemical structure of 2-dehydro-D-glucoseNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm0000686vanillateC8H7O4Chemical structure of vanillateNot available
Average167.1388Da
Monoisotopic167.0344337Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da

Displaying 1–10 of 90 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total