Schaalia odontolytica strain XH001

Gram-positiveFilamentousNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Schaalia

Description

Schaalia odontolytica strain XH001 is a Gram-positive, filamentous bacterium classified as a chemoheterotroph and a facultative anaerobe. It is primarily found in the gut of its host, Homo sapiens, where it utilizes organic compounds for energy. This strain does not exhibit mobility despite the presence of flagella, indicating a non-motile lifestyle within the intestinal environment. The optimal growth temperature for Schaalia odontolytica strain XH001 is 37°C, which aligns with the typical body temperature of humans, supporting its adaptation to the host gut. The bacterium is mesophilic, thriving within a temperature range conducive to human physiology. Notably, it has a single replicon, which may suggest a streamlined genomic organization. Schaalia odontolytica strain XH001 is associated with several severe health effects, including sepsis, empyema, and various systemic infections affecting the lungs, abdominal cavity, blood, brain, pericardial cavity, and bone marrow. In addition to these conditions, it is implicated in actinomycosis and infections of the thoracic, abdominal, pelvic, and central nervous systems. The pathogenic potential of this bacterium underscores the importance of understanding its role in human health and disease. Its presence in the gut and subsequent capability to cause serious infections highlights the complex interactions between host microbiota and opportunistic pathogens. Further elucidation of its ecological role in the human gut may enhance our comprehension of microbiome dynamics and their implications for health and disease management.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusSchaalia
SpeciesSchaalia odontolytica
Strainstrain XH001

Profile

Physiology
Gram staining propertiesPositive
ShapeFilamentous
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHost gut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Schaalia odontolytica strain XH001 contig_5, whole genome shotgun

Gene Summary

Adenine Count

395951 bp

Thymine Count

399677 bp

Guanine Count

770386 bp

Cytosine Count

770009 bp

Genome Length

2336123 bp

Protein-coding Genes

1903 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorAPY09_08060Not AvailableNegative1897190 - 189778021784.2
Trna-leuNot AvailableNot AvailablePositive1897844 - 1897920Not Available
hypothetical proteinAPY09_08070Not AvailableNegative1898054 - 18982697824.25
pyruvate kinaseAPY09_08075Not AvailableNegative1898506 - 189987049019.9
prolipoprotein diacylglyceryl transferaseAPY09_08080Not AvailableNegative1900077 - 190103634477.5
tryptophan synthase subunit alphaAPY09_08085Not AvailableNegative1901033 - 190184228266.3
tryptophan synthase subunit betaAPY09_08090Not AvailableNegative1901844 - 190313945983.3
indole-3-glycerol phosphate synthaseAPY09_08095Not AvailableNegative1903139 - 190398730160.1
anthranilate synthaseAPY09_08100Not AvailableNegative1904076 - 190560553960.6
peptidase a24APY09_08105Not AvailableNegative1905709 - 190640124420.8

Displaying genes 1641 – 1650 of 1985 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Actinomyces odontolyticus sepsisCausesPMC10294425
SepsisCausesPMC10294425
Chronic granulomatous infectionCausesPMC10843370
EmpyemaCausesPMC10843370
Lung infectionsCausesPMC10843370
Abdominal cavity infectionsCausesPMC10843370
Blood infectionsCausesPMC10843370
Brain infectionsCausesPMC10843370
Pericardial cavity infectionsCausesPMC10843370
Bone marrow infectionsCausesPMC10843370

Displaying health effects 1 – 10 of 14 in total