Mycobacterium gordonae strain CTRI 14-8773

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium gordonae strain CTRI 14-8773 is a non-tuberculous mycobacterium (NTM) notable for its presence in various habitats, including biofilms, fresh water, laboratory faucets, pipelines, soil, and water reservoirs in humidifiers, as well as well water. This strain possesses flagella and has a single replicon. This organism is of particular concern in clinical settings as it is associated with several health effects in humans, including endocarditis, pulmonary disease, and pulmonary infections, collectively referred to as NTM pulmonary disease (NTM-PD). It has been implicated in clinically significant diseases, including humidifier lung (HL), which highlights its potential to impact respiratory health, particularly in individuals who may be exposed to contaminated water systems. The presence of Mycobacterium gordonae in diverse environments, especially those connected to human activities, underscores its ecological adaptability and potential for pathogenicity. The strain's ability to thrive in biofilms and water systems suggests that it may frequently enter human environments through contaminated water sources, emphasizing the importance of monitoring water quality in healthcare and residential settings to reduce the risk of infections caused by this organism. Understanding its ecological niches can aid in developing strategies to mitigate its health impacts. The accession number for this strain is LKTM00000000.1, which can be used for further genomic studies and research.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium gordonae
Strainstrain CTRI 14-8773

Profile

Physiology
Gram staining propertiesNot Available
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbiofilms; Fresh water; laboratory faucets; pipelines; soil; water in the humidifier reservoir; well water
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mycobacterium gordonae strain CTRI 14-8773


Gene Summary

Adenine Count

1251719 bp

Thymine Count

1257773 bp

Guanine Count

2531656 bp

Cytosine Count

2516789 bp

Genome Length

7557937 bp

Protein-coding Genes

6376 genes

Non-Coding Genes

87 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AntirepressorAO501_25055Not AvailablePositive6832413 - 683320729469.9
hypothetical proteinAO501_25060Not AvailableNegative6833384 - 683371611758.1
hypothetical proteinAO501_25065Not AvailablePositive6833734 - 68339407527.36
GlutaredoxinAO501_25070Not AvailablePositive6833937 - 68342039473.23
hypothetical proteinAO501_25075Not AvailablePositive6834200 - 68344248091.77
hypothetical proteinAO501_25080Not AvailablePositive6834424 - 68346036105.06
hypothetical proteinAO501_25085Not AvailablePositive6834600 - 68348669945.69
hypothetical proteinAO501_25090Not AvailablePositive6834863 - 683556724083.0
Gp101AO501_25095Not AvailablePositive6835964 - 683666224410.5
Hypothetical proteinAO501_25100Not AvailablePositive6836759 - 683735221831.2

Displaying genes 1 – 10 of 6463 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

503 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000198tetracenomycin CC23H20O11Chemical structure of tetracenomycin CNot available
Average472.402Da
Monoisotopic472.100561464Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002634-(hydroxymethyl)benzenesulfonateC7H7O4SChemical structure of 4-(hydroxymethyl)benzenesulfonateNot available
Average187.19Da
Monoisotopic187.007053459Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da

Displaying 1–10 of 503 metabolites

Health Effects

Health ConditionRelationReference
Ntm-pdCausesPMC11100324
Pulmonary infectionCausesPMC3354412
Pulmonary diseaseCausesPMC3354412
Clinically significant diseaseCausesPMC3354412
Humidifier lungCausesPMC4589115
HlCausesPMC4589115
EndocarditisCausesPMC7642850

Displaying health effects 1 – 7 of 7 in total