Lactococcus lactis subsp. lactis strain DPC6853

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Lactococcus

Description

Lactococcus lactis subsp. lactis strain DPC6853 is a Gram-positive, cocci-shaped bacterium that typically organizes in chains. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, although it is optimal at a temperature of 40°C, which places it within the mesophilic range. The organism is non-motile and does not possess flagella, indicating a lack of mobility. This strain has a single replicon and is characterized by a single membrane. It exists as a free-living organism and has a diverse range of hosts, including Homo sapiens, Bos taurus, and various other Metazoa and plant species such as Medicago sativa. This wide host range suggests that L. lactis subsp. lactis DPC6853 may play various ecological roles across different environments. While it is classified as non-pathogenic to humans, it has been associated with several health issues, including endocarditis, peritonitis, and hepatic abscesses. This dual nature highlights its potential as a beneficial microorganism in some contexts, while also indicating that under certain conditions, it may contribute to opportunistic infections. The ecological insight from the traits of L. lactis subsp. lactis DPC6853 underscores the complexity of microbial interactions and the importance of environmental factors in determining the roles of bacteria in both health and disease. The strain's capability to inhabit multiple environments and its relationships with various hosts reflect its adaptability and significance within the microbial community.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusLactococcus
SpeciesLactococcus lactis
Strainsubsp. lactis strain DPC6853

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lactococcus lactis subsp. lactis strain DPC6853
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature40
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman; Non-pathogenic

Genome Summary

Lactococcus lactis subsp. lactis strain DPC6853


Gene Summary

Adenine Count

813113 bp

Thymine Count

816338 bp

Guanine Count

436327 bp

Cytosine Count

441295 bp

Genome Length

2507146 bp

Protein-coding Genes

2588 genes

Non-Coding Genes

138 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive784039 - 784050Not Available
IntegraseVN91_0828P96629Negative784275 - 78535741677.3
Hypothetical proteinVN91_0829Not AvailableNegative785479 - 78628228517.2
Hypothetical proteinVN91_0830Not AvailableNegative786376 - 78743140324.6
hypothetical proteinVN91_0831Not AvailableNegative787512 - 78794616870.2
Ci phage repressor proteinVN91_0832Not AvailableNegative787956 - 78830012907.2
hypothetical proteinVN91_0833Not AvailablePositive788581 - 7888119113.8
Anti-repressorVN91_0834P44189Positive788826 - 78958728969.6
Orf7VN91_0835Not AvailablePositive789600 - 78989011331.8
Hypothetical proteinVN91_0836Not AvailablePositive789892 - 7900204829.03

Displaying genes 1 – 10 of 2726 in total

Metabolites

117 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000542HgHgChemical structure of HgNot available
Average200.59Da
Monoisotopic201.9706256Da

Displaying 1–10 of 117 metabolites

Health Effects

Health ConditionRelationReference
EndocarditisCausesPMC10064683
PeritonitisCausesPMC10064683
Intra-abdominal infectionsCausesPMC10064683
Infectious endocarditisCausesPMC10064683
Hepatic abscessCausesPMC10064683
Liver abscessesCausesPMC10064683
MastitisCausesPMC13343983
LactococcosisCausesPMC12824592

Displaying health effects 1 – 8 of 8 in total