Leptospira interrogans serovar Lai strain SR61

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Leptospiria

Order

Leptospirales

Family

Leptospiraceae

Genus

Leptospira

Description

Leptospira interrogans serovar Lai strain SR61 is a gram-negative, aerobic bacterium characterized by its spirilla shape and the presence of flagella, which contribute to its motility. This strain is mesophilic, with an optimal growth temperature of 28°C. Notably, it possesses a single replicon and is composed of two membranes, which is typical for gram-negative organisms. This strain is associated with various hosts, including Homo sapiens (humans), Metazoa (multicellular animals), and Cricetinae (hamsters). Leptospira interrogans is pathogenic, causing leptospirosis, a disease that can lead to severe health complications in infected hosts. The habitat of Leptospira interrogans serovar Lai strain SR61 is primarily host-associated, suggesting that it thrives within the biological environments of its hosts. The bacterium's ability to adapt to the host's internal conditions is crucial for its survival and pathogenicity. Understanding the characteristics of this strain provides insight into its ecological role and health impacts. Leptospira interrogans serovar Lai strain SR61 exemplifies the complex interactions between pathogens and their hosts, highlighting the importance of studying microbial traits to comprehend their implications in diseases like leptospirosis. Further research into this strain could enhance our understanding of its transmission dynamics and inform public health strategies to mitigate its impact on affected populations.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassLeptospiria
OrderLeptospirales
FamilyLeptospiraceae
GenusLeptospira
SpeciesLeptospira interrogans
Strainserovar Lai strain SR61

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Leptospira interrogans serovar Lai strain SR61
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature28
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Cricetinae
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Leptospira interrogans serovar Lai strain SR61


Gene Summary

Adenine Count

1594408 bp

Thymine Count

1577923 bp

Guanine Count

851040 bp

Cytosine Count

868211 bp

Genome Length

4891582 bp

Protein-coding Genes

4085 genes

Non-Coding Genes

58 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Predicted transposaseIQ65_21615Not AvailableNegative4367720 - 436826621420.7
Hypothetical proteinIQ65_21620Not AvailableNegative4368306 - 436904627772.7
Putative major capsid proteinIQ65_21625Not AvailableNegative4369111 - 437056253898.2
hypothetical proteinIQ65_21630Not AvailableNegative4370559 - 437125126223.3
Hypothetical proteinIQ65_21635Not AvailableNegative4371244 - 437217935775.2
Kelch repeat proteinIQ65_21645Not AvailableNegative4372755 - 437400544468.4
hypothetical proteinIQ65_21650Not AvailableNegative4374312 - 437469814155.9
Hypothetical proteinIQ65_21655Not AvailableNegative4374744 - 437629159152.4
Hypothetical proteinIQ65_21660Not AvailableNegative4376310 - 437699025479.2
Baseplate j family proteinIQ65_21670Not AvailablePositive4378953 - 438014343584.3

Displaying genes 1 – 10 of 4143 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

71 records
Metabolite IDMetabolite nameStructureCAS number
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014182Vaccenic acidC18H34O2Chemical structure of Vaccenic acidNULL
Average282.468Da
Monoisotopic282.255880335Da
BASm0014222DiethanolamineC4H11NO2Chemical structure of DiethanolamineNULL
Average105.1356Da
Monoisotopic105.078978601Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0017395CDP-DG(16:0/18:1(9Z))C46H83N3O15P2Chemical structure of CDP-DG(16:0/18:1(9Z))NULL
Average980.124Da
Monoisotopic979.529942981Da
BASm0017399CDP-DG(18:0/18:1(9Z))C48H87N3O15P2Chemical structure of CDP-DG(18:0/18:1(9Z))NULL
Average1008.178Da
Monoisotopic1007.561243109Da
BASm0017409PA(16:0/18:1(9Z))C37H71O8PChemical structure of PA(16:0/18:1(9Z))NULL
Average674.941Da
Monoisotopic674.488656244Da
BASm0017415PA(18:1(9Z)/18:1(9Z))C39H73O8PChemical structure of PA(18:1(9Z)/18:1(9Z))14268-17-8
Average700.979Da
Monoisotopic700.504306309Da

Displaying 1–10 of 71 metabolites

Health Effects

Health ConditionRelationReference
LeptospirosisCausesPMC5486853
LeptospirosisCausesPMC10645364
LeptospirosisCausesPMC12943098
LeptospirosisCausesPMC3799732

Displaying health effects 1 – 4 of 4 in total