Mycobacterium tuberculosis strain 2926STDY5723586

Gram-positiveRodNon-motileAerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycobacterium

Description

Mycobacterium tuberculosis strain 2926STDY5723586 is a gram-positive, rod-shaped bacterium that is classified as a chemoorganotroph, deriving its energy from organic compounds. This strain is aerobic, requiring oxygen for growth, and is mesophilic, with an optimal temperature of 37°C, which aligns with the average human body temperature, indicating its adaptation to host environments. This strain is notable for its lack of mobility, as it does not possess flagella. It has a single replicon and a single membrane, characteristics typical of the Mycobacterium genus. M. tuberculosis strain 2926STDY5723586 is primarily associated with humans but is also capable of infecting a range of other hosts, including various domesticated animals such as Bos taurus (cattle), Sus scrofa (pigs), Canis lupus familiaris (dogs), and Felis catus (cats), as well as other metazoans and members of the Equidae family (horses). The strain is significant in public health as it is linked to several serious health conditions, including acute bacterial meningitis, tuberculosis (TB) in humans and animals, and specifically bovine tuberculosis (bTB). The diverse host range suggests that M. tuberculosis strain 2926STDY5723586 has evolved mechanisms that allow it to thrive in different biological environments, highlighting its ecological adaptability and the potential for zoonotic transmission. Understanding the ecology and pathogenicity of this strain is crucial for developing effective prevention and treatment strategies against tuberculosis.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycobacterium
SpeciesMycobacterium tuberculosis
Strainstrain 2926STDY5723586

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Mycobacterium tuberculosis strain 2926STDY5723586
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Mycobacterium tuberculosis strain 2926STDY5723586


Gene Summary

Adenine Count

1737760 bp

Thymine Count

1737998 bp

Guanine Count

2456134 bp

Cytosine Count

2458291 bp

Genome Length

8403077 bp

Protein-coding Genes

7501 genes

Non-Coding Genes

481 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Error-prone lesion bypass dna polymerase vSAMEA2682835_00004Not AvailablePositive2290 - 355246845.4
Trna-pro;Not AvailableNot AvailablePositive3680 - 3756Not Available
Sh3 domain-containing proteinSAMEA2682835_00005Not AvailablePositive3894 - 447820471.3
Trna-thr;Not AvailableNot AvailablePositive3900 - 3975Not Available
Trna-tyr;Not AvailableNot AvailablePositive3992 - 4076Not Available
Trna-gly;Not AvailableNot AvailablePositive4179 - 4253Not Available
Trna-thr;Not AvailableNot AvailablePositive4260 - 4335Not Available
udp-d-galactose:(glucosyl)lipopolysaccharide- 1%2 c6-d-galactosyltransferaseSAMEA2682835_00006Not AvailableNegative4576 - 565240003.9
Trna-pro;Not AvailableNot AvailablePositive5558 - 5633Not Available
Trna-lys;Not AvailableNot AvailablePositive5647 - 5720Not Available

Displaying genes 1 – 10 of 7982 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

754 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm00005166-deoxyerythronolide BC21H38O6Chemical structure of 6-deoxyerythronolide BNot available
Average386.5228Da
Monoisotopic386.2668389Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da

Displaying 1–10 of 754 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
TuberculosisCausesPMC7609860
TuberculosisCausesPMC11206017
TuberculosisCausesPMC11483126
TbCausesPMC11483126
Lung diseasesCausesPMC11716203
TuberculosisCausesPMC11716203
TbCausesPMC11716203
TuberculosisCausesPMC11807137
Bovine tuberculosisCausesPMC11920072

Displaying health effects 1 – 10 of 38 in total