Chlamydia trachomatis

Gram-negativeRodNon-motile

Kingdom

Pseudomonadati

Phylum

Chlamydiota

Class

Chlamydiia

Order

Chlamydiales

Family

Chlamydiaceae

Genus

Chlamydia

Description

Chlamydia trachomatis is a Gram-negative bacterium characterized by its rod shape and lack of mobility, as it does not possess flagella. This organism is classified as mesophilic, with an optimal growth temperature of 37°C. C. trachomatis is associated with a host habitat, specifically infecting Homo sapiens and Macaca mulatta. It has a complex cellular structure consisting of two membranes and three replicons. C. trachomatis exhibits a symbiotic biotic relationship with its hosts, meaning it lives in close association with them. However, this relationship can have detrimental health effects. In humans, infection with C. trachomatis can lead to a range of health issues, including infertility, male urethritis, urethritis, pelvic inflammatory disease (PID), and ectopic pregnancy. These health complications highlight the significant public health concern posed by this bacterium. Given its mode of transmission and the diseases it causes, Chlamydia trachomatis serves as an important model for studying host-pathogen interactions and the impact of bacterial infections on reproductive health. Understanding the specific relationships and effects of C. trachomatis in its hosts is crucial for developing effective treatment and prevention strategies. The presence of this bacterium in both humans and non-human primates suggests a long-standing evolutionary relationship, emphasizing the need for ongoing research in microbiology and infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumChlamydiota
ClassChlamydiia
OrderChlamydiales
FamilyChlamydiaceae
GenusChlamydia
SpeciesChlamydia trachomatis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Chlamydia trachomatis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Macaca mulatta, Vertebrata
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Chlamydia trachomatis


Gene Summary

Adenine Count

629927 bp

Thymine Count

629397 bp

Guanine Count

395465 bp

Cytosine Count

399342 bp

Genome Length

2082669 bp

Protein-coding Genes

1444 genes

Non-Coding Genes

44 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribonucleoside-diphosphate reductase subunit alphaERS015772_00001O84834Positive728 - 3871119472.0
16s ribosomal rnaNot AvailableNot AvailablePositive1811 - 3351Not Available
23s ribosomal rnaNot AvailableNot AvailablePositive3607 - 6541Not Available
ribonucleotide-diphosphate reductase subunit betaERS015772_00002O84835Positive3909 - 494940446.6
Trna-valNot AvailableNot AvailablePositive5877 - 5950Not Available
sam-dependent methyltransferaseERS015772_00004O34614Positive6005 - 658621379.7
5s ribosomal rnaNot AvailableNot AvailablePositive6663 - 6776Not Available
udp-n-acetylenolpyruvoylglucosamine reductaseERS015772_00005Q3KKK8Negative6583 - 745831622.3
n utilization substance protein bERS015772_00006Q3KKK7Negative7591 - 837929438.4
bacterial protein translation initiation factor 3 (if-3)ERS015772_00007O84840Positive8475 - 905621770.7

Displaying genes 1 – 10 of 5077 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

149 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00019783-(4-hydroxyphenyl)pyruvateC9H7O4Chemical structure of 3-(4-hydroxyphenyl)pyruvateNot available
Average179.1495Da
Monoisotopic179.034433712Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da

Displaying 1–10 of 149 metabolites

Health Effects

Health ConditionRelationReference
Male urethritisCausesPMC13191610
UrethritisCausesPMC13191610
Pelvic inflammatory diseaseCausesPMC3602122
Ectopic pregnancyCausesPMC3602122
InfertilityCausesPMC3602122
PidCausesPMC3602122
Ocular and urogenital infectionsCausesPMC11249467
TrachomaCausesPMC11249467
Sexually transmitted diseasesCausesPMC11249467
Ocular infectionsCausesPMC11925236

Displaying health effects 1 – 10 of 14 in total