Cutibacterium granulosum DSM 20700

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium granulosum DSM 20700 is a Gram-positive, mesophilic bacterium that inhabits the host epidermis. This species is classified as a chemoheterotroph, deriving its energy from organic compounds. C. granulosum is characterized by its rod shape and is non-motile, lacking the ability to move independently due to the absence of flagella. However, it is noted that this bacterium does have flagella present, which may play a role in its ecological interactions. C. granulosum is strictly anaerobic, meaning it thrives in environments devoid of oxygen. This characteristic indicates it may inhabit niches on the skin that are less exposed to oxygen, possibly contributing to the complex microbial communities found on human skin. The genomic structure of C. granulosum is notable, with two replicons identified in its genome. This trait may have implications for its adaptability and genetic diversity within its ecological niche. Overall, the presence of Cutibacterium granulosum in the host epidermis underscores the importance of anaerobic bacteria in human skin microbiota, potentially influencing skin health and microbial balance. The insights into its metabolic capabilities and habitat reinforce the role of this bacterium in maintaining the skin's ecological equilibrium.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium granulosum
StrainDSM 20700

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium granulosum DSM 20700
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHost epidermis
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Cutibacterium granulosum DSM 20700 contig372, whole genome shotgun

Gene Summary

Adenine Count

378711 bp

Thymine Count

385102 bp

Guanine Count

687201 bp

Cytosine Count

677220 bp

Genome Length

2128234 bp

Protein-coding Genes

1950 genes

Non-Coding Genes

53 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter, permease proteinH641_07667Not AvailablePositive1660025 - 166057619861.5
putative histidine transport atp-binding protein hispH641_07672Not AvailablePositive1660573 - 166144531113.5
s4 domain-containing proteinH641_07677Not AvailablePositive1661456 - 16616838217.75
membrane atpase/protein kinaseH641_07682Not AvailableNegative1661687 - 166271236643.9
methylmalonyl-coa mutaseH641_07687Not AvailableNegative1663023 - 166521279954.2
methylmalonyl-coa mutase, small subunitH641_07692Not AvailableNegative1665209 - 166711668301.5
hydrolase, alpha/beta fold family proteinH641_07697Not AvailableNegative1667719 - 166822218443.0
hydrolase, alpha/beta fold family proteinH641_07702Not AvailableNegative1668224 - 166862014606.5
putative lytr family regulatory proteinH641_07707Not AvailableNegative1668700 - 166978839723.2
sugar transferaseH641_07712Not AvailablePositive1670047 - 167140549911.7

Displaying genes 1561 – 1570 of 3827 in total

Metabolites

444 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 444 metabolites

Health Effects

No health effects information available for this bacterium.