Cutibacterium granulosum DSM 20700

RodNon-motileanaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium granulosum DSM 20700 is a Gram-positive, mesophilic bacterium that inhabits the host epidermis. This species is classified as a chemoheterotroph, deriving its energy from organic compounds. C. granulosum is characterized by its rod shape and is non-motile, lacking the ability to move independently due to the absence of flagella. However, it is noted that this bacterium does have flagella present, which may play a role in its ecological interactions. C. granulosum is strictly anaerobic, meaning it thrives in environments devoid of oxygen. This characteristic indicates it may inhabit niches on the skin that are less exposed to oxygen, possibly contributing to the complex microbial communities found on human skin. The genomic structure of C. granulosum is notable, with two replicons identified in its genome. This trait may have implications for its adaptability and genetic diversity within its ecological niche. Overall, the presence of Cutibacterium granulosum in the host epidermis underscores the importance of anaerobic bacteria in human skin microbiota, potentially influencing skin health and microbial balance. The insights into its metabolic capabilities and habitat reinforce the role of this bacterium in maintaining the skin's ecological equilibrium.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium granulosum
StrainDSM 20700

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cutibacterium granulosum DSM 20700
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsanaerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHost epidermis
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Cutibacterium granulosum DSM 20700 Contig_53_71.3479, whole genome

Gene Summary

Adenine Count

392546 bp

Thymine Count

382750 bp

Guanine Count

689993 bp

Cytosine Count

700045 bp

Genome Length

2165334 bp

Protein-coding Genes

1772 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative holinH641_08150Not AvailableNegative1764870 - 176525613112.5
Putative endolysinH641_08155Not AvailableNegative1765257 - 176610531285.8
Putative collagen-like minor tail proteinH641_08160Not AvailableNegative1766512 - 176692214274.8
Hypothetical proteinH641_08165Not AvailableNegative1766906 - 17671609006.82
hypothetical proteinH641_08170Not AvailableNegative1767171 - 17674168252.04
Hypothetical proteinH641_08175Not AvailableNegative1767413 - 176773011209.2
hypothetical proteinH641_08180Not AvailableNegative1767727 - 17678253416.91
hypothetical proteinH641_08185Not AvailablePositive1768329 - 176883217851.1
Putative antirepressorH641_08190Not AvailableNegative1768911 - 176967228503.2
hypothetical proteinH641_08195Not AvailablePositive1769714 - 177004611974.2

Displaying genes 1 – 10 of 3827 in total

Metabolites

146 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001462ubiquinone-0C9H10O4Chemical structure of ubiquinone-0605-94-7
Average182.1733Da
Monoisotopic182.057908808Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm00016962-heptyl-3-hydroxy-4(1H)-quinoloneC16H21NO2Chemical structure of 2-heptyl-3-hydroxy-4(1H)-quinoloneNot available
Average259.349Da
Monoisotopic259.15722892Da
BASm0002146(1R,2S)-1,2-dihydronaphthalene-1,2-diolC10H10O2Chemical structure of (1R,2S)-1,2-dihydronaphthalene-1,2-diolNot available
Average162.1852Da
Monoisotopic162.0680796Da
BASm0002593(2E)-dodecenoyl-CoAC33H52N7O17P3SChemical structure of (2E)-dodecenoyl-CoA1066-12-2
Average943.789Da
Monoisotopic943.2353235Da

Displaying 1–10 of 146 metabolites

Health Effects

No health effects information available for this bacterium.