Akkermansia muciniphila CAG:154

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila CAG:154 is a Gram-negative, anaerobic cocci bacterium typically found in host-associated environments. This species is characterized by its unique cell arrangement, which can be observed as pairs or singles. Notably, it lacks mobility, indicating that it does not possess flagella despite their presence in the species classification. A. muciniphila CAG:154 thrives at an optimal temperature of 37°C, falling within the mesophilic temperature range, which is conducive for growth in warm-blooded hosts. It has a biotic relationship classified as free-living and features a cell structure comprising two membranes and a single replicon. The ecological significance of A. muciniphila lies in its potential role in the gut microbiome, where it is believed to contribute to the maintenance of gut barrier integrity and modulation of host immune responses. Its anaerobic nature suggests it plays a role in fermentation processes within the gastrointestinal tract, which can influence nutrient absorption and overall host health. Given its habitat and traits, A. muciniphila CAG:154 may be essential for establishing a balanced microbial community, potentially impacting metabolic health and disease resistance in its host. This bacterium exemplifies the complex interactions within host-associated microbiomes and highlights the importance of specific microbial taxa in maintaining health. Its unique characteristics make it a significant subject of study in microbiology and its implications for host health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainCAG:154

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila CAG:154
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila CAG:154


Gene Summary

Adenine Count

611310 bp

Thymine Count

598676 bp

Guanine Count

750010 bp

Cytosine Count

757335 bp

Genome Length

2717442 bp

Protein-coding Genes

2376 genes

Non-Coding Genes

47 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
unknownBN502_00001Not AvailableNegative422 - 75413109.8
potassium-transporting atpase a chain 2BN502_00002Not AvailablePositive1944 - 365062335.0
potassium-transporting atpase b chain 2BN502_00003Not AvailablePositive3735 - 576872539.9
potassium-transporting atpase c chain 2BN502_00004Not AvailablePositive5788 - 637221056.4
osmosensitive k channel his kinase sensorBN502_00005Not AvailablePositive6553 - 768042788.4
putative uncharacterized proteinBN502_00006Not AvailablePositive8033 - 901936494.0
putative uncharacterized proteinBN502_00007Not AvailablePositive9178 - 93907394.49
beta-lactamase domain proteinBN502_00008Not AvailablePositive9556 - 1039530281.8
rna polymerase sigma-24 subunit ecf subfamilyBN502_00009Not AvailablePositive10421 - 1101722690.5
serine/threonine protein kinaseBN502_00010Not AvailablePositive11014 - 1331786141.9

Displaying genes 1 – 10 of 2423 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.