Helicobacter pylori PeCan18

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori PeCan18 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This organism is typically found in host-associated habitats, indicating a close association with its hosts, commonly human gastric tissues. Its optimal growth temperature is 37°C, which aligns with the physiological conditions typically found in the stomach. H. pylori PeCan18 exhibits a unique cellular arrangement, existing as single cells rather than in clusters or chains. It possesses a single replicon and has a double membrane structure, consistent with its classification as a Gram-negative bacterium. The bacterium is classified as mesophilic, thriving within a temperature range that accommodates human body temperatures. In terms of mobility, H. pylori PeCan18 does not exhibit movement through self-propulsion but relies on external factors for dispersion. Its biotic relationship is categorized as free-living, which suggests that while it is primarily associated with hosts, it can survive independently in certain conditions. The presence of H. pylori in the human stomach is significant, as it is known to be associated with various gastrointestinal diseases, including gastritis and peptic ulcers. Understanding the traits of H. pylori PeCan18 enhances our knowledge of its ecological niche and potential impacts on human health, highlighting the importance of host-associated microbial communities in maintaining gastric homeostasis.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainPeCan18

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori PeCan18
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori PeCan18


Gene Summary

Adenine Count

502467 bp

Thymine Count

510245 bp

Guanine Count

323912 bp

Cytosine Count

324061 bp

Genome Length

1660685 bp

Protein-coding Genes

1537 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcription antitermination factor nusbHPPC18_RS00005Not AvailableNegative11 - 42715522.0
6,7-dimethyl-8-ribityllumazine synthaseHPPC18_RS00010Not AvailableNegative429 - 89916927.6
3-deoxy-8-phosphooctulonate synthaseHPPC18_RS00015Not AvailableNegative909 - 173930209.4
carbonic anhydraseHPPC18_RS00020Not AvailableNegative1726 - 239125735.7
orotidine-5'-phosphate decarboxylaseHPPC18_RS00025Not AvailablePositive2513 - 319625211.9
pantoate--beta-alanine ligaseHPPC18_RS00030Not AvailablePositive3197 - 402731146.9
Trna-gluNot AvailableNot AvailablePositive4041 - 4116Not Available
Trna-aspNot AvailableNot AvailablePositive4176 - 4252Not Available
Trna-valNot AvailableNot AvailablePositive4303 - 4378Not Available
Trna-gluNot AvailableNot AvailablePositive4421 - 4495Not Available

Displaying genes 1 – 10 of 1582 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

24 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002026acrylateC3H3O2Chemical structure of acrylate10344-93-1
Average71.056Da
Monoisotopic71.013852917Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm0003276S-(5-deoxy-D-ribos-5-yl)-L-homocysteineC9H17NO6SChemical structure of S-(5-deoxy-D-ribos-5-yl)-L-homocysteine15912-98-8
Average267.299Da
Monoisotopic267.077658Da
BASm00033514-methyl-5-(2-phosphooxyethyl)-thiazoleC6H8NO4PSChemical structure of 4-methyl-5-(2-phosphooxyethyl)-thiazoleNot available
Average221.17Da
Monoisotopic220.9922631Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–10 of 24 metabolites

Health Effects

No health effects information available for this bacterium.