Brachyspira pilosicoli B2904

Gram-negativeSpirillaNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Spirochaetia

Order

Brachyspirales

Family

Brachyspiraceae

Genus

Brachyspira

Description

Brachyspira pilosicoli B2904 is a Gram-negative, mesophilic bacterium characterized by its spirilla shape. It is a chemoorganotroph, deriving energy from organic compounds, and exhibits anaerobic growth, indicating that it does not require oxygen for survival. This species has a single replicon and is noted for its symbiotic relationships within its ecological niche. Flagella are present, which may play a role in its movement within a host's intestines, although the bacterium is classified as non-motile in the conventional sense. The presence of flagella suggests a potential for limited motility in specific contexts, possibly aiding in colonization or maintaining proximity to suitable substrates. Brachyspira pilosicoli B2904 is associated with intestinal spirochaetosis, a condition that can affect various animal species, including humans. This association indicates that the bacterium could be significant in understanding gastrointestinal health and disease dynamics within host organisms. The ecological role of Brachyspira pilosicoli B2904 underscores its importance in the gut microbiome, where it may contribute to the balance of microbial communities and influence host metabolism and immune responses. The understanding of its symbiotic relationships and effects on health could inform both veterinary and medical microbiology, particularly in the management of gut-related health issues. The accession number NC_018607.1 provides a reference for further genomic analysis of this bacterium.

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassSpirochaetia
OrderBrachyspirales
FamilyBrachyspiraceae
GenusBrachyspira
SpeciesBrachyspira pilosicoli
StrainB2904

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Brachyspira pilosicoli B2904
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatNot Available
Biotic relationshipSymbiotic
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Brachyspira pilosicoli B2904, complete sequence.

Gene Summary

Adenine Count

999370 bp

Thymine Count

997652 bp

Guanine Count

391254 bp

Cytosine Count

377186 bp

Genome Length

2765477 bp

Protein-coding Genes

2587 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2009470 - 2009482Not Available
Tail tape measure proteinB2904_RS09230Not AvailableNegative2021058 - 2024531126933.0
hypothetical proteinB2904_RS09235Not AvailableNegative2024556 - 20247417257.63
hypothetical proteinB2904_RS09240Not AvailableNegative2024788 - 202514713714.6
hypothetical proteinB2904_RS09245Not AvailableNegative2025172 - 202626039477.4
hypothetical proteinB2904_RS09250Not AvailableNegative2026272 - 202664014072.5
Hypothetical proteinB2904_RS09255Not AvailableNegative2026637 - 202710717349.8
head-tail adaptor proteinB2904_RS09260Not AvailableNegative2027109 - 202745013160.8
head-tail connector proteinB2904_RS09265Not AvailableNegative2027447 - 202781213558.8
Phage major capsid proteinB2904_RS09270Not AvailableNegative2027839 - 202914048408.3

Displaying genes 1 – 10 of 2637 in total

Metabolites

614 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da

Displaying 1–10 of 614 metabolites

Health Effects

Health ConditionRelationReference
Intestinal spirochaetosisCausesPMC6375133

Displaying health effects 1 – 1 of 1 in total