Edwardsiella ictaluri 93-146

The disease caused by Edwardsiella ictaluri, enteric septicemia of catfish (ESC), is the most economically important disease of farm-raised channel catfish, which is the largest aquaculture industry in the United States. Functional predictions for the ORFs indicate that the physiology of E. ictaluri is similar in many respects to other members of the Enterobacteriaceae, including Escherichia coli O157:H7, Salmonella enterica, Yersinia pestis, and Erwinia carotovora. However, E. ictaluri does have some unique features; for example, its genome contains a higher number of genes involved in DNA recombination, replication, and repair, protein stabilization and two-component regulatory systems. This may indicate that E. ictaluri is adapted to survival in more stressful or diverse environments than other Enterobacteriaceae species. The genome has 203 transposable elements, which is considerably higher than the other four species. This is surprising because E. ictaluri only has one serovar and is generally considered to be phenotypically homogenous (adapted from http://www.miangel.msstate.edu/research/eigenome.html). (EBI Integr8)