Shigella flexneri 2002017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri 2002017 is a gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a chemoheterotroph, and can colonize all body sites in various species, including humans, and is a facultative anaerobe. As a gram-negative bacterium, Shigella flexneri 2002017 has a distinctive outer membrane containing lipopolysaccharides, which plays a crucial role in its pathogenicity. Its rod-shaped morphology allows for efficient movement and invasion of host cells. The mesophilic temperature preference of this microbe enables it to thrive in temperatures between 20-45°C, making it well-suited to infecting human hosts. As a chemoheterotroph, Shigella flexneri 2002017 relies on organic compounds for energy and carbon, which it obtains from its host environment. This microbe can infect all body sites, including the gastrointestinal tract, and is capable of surviving in various species. Its classification as a facultative anaerobe means it can grow in both aerobic and anaerobic conditions, allowing it to adapt to different environments within the host. The ability of Shigella flexneri 2002017 to invade and multiply within host cells leads to severe diarrhea and dysentery. This microbe has been implicated in large outbreaks of foodborne and waterborne illnesses, and its ability to develop antibiotic resistance makes it a significant public health concern, with ongoing research focused on developing effective treatments and preventative measures against Shigella flexneri 2002017 infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strain2002017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri 2002017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityNot Available

Genome Summary

Shigella flexneri 2002017 plasmid pSFxv_2, complete sequence.

Gene Summary

Adenine Count

1899 bp

Thymine Count

1935 bp

Guanine Count

1546 bp

Cytosine Count

1470 bp

Genome Length

6850 bp

Protein-coding Genes

8 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
trna uridine-5-carboxymethylaminomethyl(34) synthesis gtpase mnmeSFXV_RS21040Q0SYP6Negative3888931 - 389029549251.8
membrane protein insertase yidcSFXV_RS21045P59783Negative3890401 - 389204761557.5
membrane protein insertion efficiency factor yiddSFXV_RS21050B7MGC6Negative3892050 - 38923079381.61
ribonuclease p protein componentSFXV_RS21055A7ZTR0Negative3892271 - 389263013790.0
50s ribosomal protein l34SFXV_RS21060A7ZTQ9Negative3892647 - 38927875380.74
protein ysddSFXV_RS30925P0DPP8Negative3893017 - 38930973111.7
chromosomal replication initiator protein dnaaSFXV_RS21065A7ZTQ8Positive3893394 - 389479752500.7
dna polymerase iii subunit betaSFXV_RS21070P0A990Positive3894802 - 389590240605.1
dna replication/repair protein recfSFXV_RS21075Q7BZ80Positive3895902 - 389697540560.4
dna topoisomerase (atp-hydrolyzing) subunit bSFXV_RS21080P0AES7Positive3897004 - 389941889955.0

Displaying genes 4011 – 4020 of 5037 in total

Metabolites

495 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000686vanillateC8H7O4Chemical structure of vanillateNot available
Average167.1388Da
Monoisotopic167.0344337Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 495 metabolites

Health Effects

No health effects information available for this bacterium.