Shigella flexneri 2002017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri 2002017 is a gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a chemoheterotroph, and can colonize all body sites in various species, including humans, and is a facultative anaerobe. As a gram-negative bacterium, Shigella flexneri 2002017 has a distinctive outer membrane containing lipopolysaccharides, which plays a crucial role in its pathogenicity. Its rod-shaped morphology allows for efficient movement and invasion of host cells. The mesophilic temperature preference of this microbe enables it to thrive in temperatures between 20-45°C, making it well-suited to infecting human hosts. As a chemoheterotroph, Shigella flexneri 2002017 relies on organic compounds for energy and carbon, which it obtains from its host environment. This microbe can infect all body sites, including the gastrointestinal tract, and is capable of surviving in various species. Its classification as a facultative anaerobe means it can grow in both aerobic and anaerobic conditions, allowing it to adapt to different environments within the host. The ability of Shigella flexneri 2002017 to invade and multiply within host cells leads to severe diarrhea and dysentery. This microbe has been implicated in large outbreaks of foodborne and waterborne illnesses, and its ability to develop antibiotic resistance makes it a significant public health concern, with ongoing research focused on developing effective treatments and preventative measures against Shigella flexneri 2002017 infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strain2002017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri 2002017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityNot Available

Genome Summary

Shigella flexneri 2002017 plasmid pSFxv_2, complete sequence.

Gene Summary

Adenine Count

1899 bp

Thymine Count

1935 bp

Guanine Count

1546 bp

Cytosine Count

1470 bp

Genome Length

6850 bp

Protein-coding Genes

8 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rna polymerase factor sigma-54SFXV_RS18365P24255Positive3376918 - 337835154010.9
ribosome hibernation promoting factorSFXV_RS18370P0AFX2Positive3378374 - 337866110750.9
pts iia-like nitrogen regulatory protein ptsnSFXV_RS18375P69829Positive3378779 - 337927017960.6
rnase adapter rapzSFXV_RS18380A7ZSA4Positive3379316 - 338017032494.2
pts phosphocarrier protein nprSFXV_RS18385P0A9N2Positive3380167 - 33804399810.71
phop regulatory network protein yrblSFXV_RS18390P64610Positive3380652 - 338128424346.4
inosine/xanthosine triphosphataseSFXV_RS18395A7ZSA7Negative3381281 - 338200826968.7
isoprenoid biosynthesis glyoxalase elbbSFXV_RS18400P0ABU5Negative3382005 - 338265822982.9
aerobic respiration two-component sensor histidine kinase arcbSFXV_RS18405P0AEC3Negative3382888 - 338522487988.0
tigr01212 family radical sam proteinSFXV_RS18410P0ADW7Negative3385320 - 338624934638.6

Displaying genes 3511 – 3520 of 5037 in total

Metabolites

495 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000686vanillateC8H7O4Chemical structure of vanillateNot available
Average167.1388Da
Monoisotopic167.0344337Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 495 metabolites

Health Effects

No health effects information available for this bacterium.