Shigella flexneri 2002017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella flexneri 2002017 is a gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a chemoheterotroph, and can colonize all body sites in various species, including humans, and is a facultative anaerobe. As a gram-negative bacterium, Shigella flexneri 2002017 has a distinctive outer membrane containing lipopolysaccharides, which plays a crucial role in its pathogenicity. Its rod-shaped morphology allows for efficient movement and invasion of host cells. The mesophilic temperature preference of this microbe enables it to thrive in temperatures between 20-45°C, making it well-suited to infecting human hosts. As a chemoheterotroph, Shigella flexneri 2002017 relies on organic compounds for energy and carbon, which it obtains from its host environment. This microbe can infect all body sites, including the gastrointestinal tract, and is capable of surviving in various species. Its classification as a facultative anaerobe means it can grow in both aerobic and anaerobic conditions, allowing it to adapt to different environments within the host. The ability of Shigella flexneri 2002017 to invade and multiply within host cells leads to severe diarrhea and dysentery. This microbe has been implicated in large outbreaks of foodborne and waterborne illnesses, and its ability to develop antibiotic resistance makes it a significant public health concern, with ongoing research focused on developing effective treatments and preventative measures against Shigella flexneri 2002017 infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella flexneri
Strain2002017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Shigella flexneri 2002017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs-Singles
SporulationNonsporulating
Energy source Chemoorganotroph
PathogenicityNot Available

Genome Summary

Shigella flexneri 2002017 plasmid pSFxv_2, complete sequence.

Gene Summary

Adenine Count

1899 bp

Thymine Count

1935 bp

Guanine Count

1546 bp

Cytosine Count

1470 bp

Genome Length

6850 bp

Protein-coding Genes

8 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ni/fe-hydrogenase cytochrome b subunitSFXV_RS17300P37180Negative3176020 - 317719843562.6
hydrogenase 2 operon protein hybaSFXV_RS17305P0AAJ9Negative3177188 - 317817436005.0
hydrogenase 2 small subunitSFXV_RS17310P69743Negative3178177 - 317929539669.3
duf2623 family protein yghwSFXV_RS17320P64576Negative3179484 - 317977110946.1
yghx family hydrolaseSFXV_RS17325Q7DFU6Negative3179890 - 318077732640.7
l-glyceraldehyde 3-phosphate reductaseSFXV_RS17330Q8X529Positive3180934 - 318197438816.3
tigr00645 family proteinSFXV_RS17335Q7UBK4Negative3182014 - 318250818656.4
nadp(+)-dependent aldehyde reductaseSFXV_RS17340P0AG85Positive3182699 - 318358331489.8
tonb system transport protein exbdSFXV_RS17345P0ABV4Negative3183855 - 318428015527.9
tol-pal system-associated acyl-coa thioesteraseSFXV_RS17350P0ABU8Negative3184287 - 318502126315.0

Displaying genes 3301 – 3310 of 5037 in total

Metabolites

495 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000686vanillateC8H7O4Chemical structure of vanillateNot available
Average167.1388Da
Monoisotopic167.0344337Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 495 metabolites

Health Effects

No health effects information available for this bacterium.