Roseburia hominis A2-183

Gram-negativeRodAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia hominis A2-183 is a microorganism that thrives in a mesophilic environment, with a temperature preference category of 25-45°C. As a heterotroph, it obtains its energy by breaking down complex organic molecules. The energy production process employed by Roseburia hominis A2-183 is fermentation, where it converts glucose into lactate and ethanol. This unique metabolism allows it to thrive in a variety of environments. Roseburia hominis A2-183 is gram-positive, indicating the presence of a thick peptidoglycan layer in its cell wall. The bacterium has a rod-like shape, with a length of approximately 3-6 micrometers. It is commonly found in the gastrointestinal tract of humans, where it plays a crucial role in the degradation of complex polysaccharides and the production of short-chain fatty acids. Roseburia hominis A2-183 is an obligate anaerobe, meaning it is unable to survive in the presence of oxygen. In fact, the bacterium is sensitive to even small amounts of oxygen, which can inhibit its growth and metabolic activities. Its anaerobic lifestyle allows it to thrive in environments where oxygen is limited or absent, such as the gastrointestinal tract. One of the most fascinating aspects of Roseburia hominis A2-183 is its ability to produce a unique mixture of short-chain fatty acids, including butyrate, acetate, and propionate. These compounds play a crucial role in the maintenance of gut health, serving as energy sources for the host and influencing the local immune responses. Further studies on Roseburia hominis A2-183 have revealed that it is capable of degrading a wide range of dietary fibers, including pectin, xylan, and arabinan. This ability allows it to play a crucial role in the degradation of complex plant material and the production of bioactive compounds. Overall, Roseburia hominis A2-183 is a remarkable microorganism that has adapted to thrive in the human gut, where it plays a vital role in maintaining our overall health and well-being. Its unique metabolic processes and ability to produce bioactive compounds make it a fascinating subject for further study and exploration.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia hominis
StrainA2-183

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Roseburia hominis A2-183
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut microbiota; human feces
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Roseburia hominis A2-183, complete sequence.

Gene Summary

Adenine Count

918915 bp

Thymine Count

931143 bp

Guanine Count

859982 bp

Cytosine Count

882085 bp

Genome Length

3592125 bp

Protein-coding Genes

3277 genes

Non-Coding Genes

74 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetyltransferaseRHOM_RS01135Not AvailablePositive267460 - 26820628501.1
laci family dna-binding transcriptional regulatorRHOM_RS01140Not AvailablePositive268707 - 26971738224.0
mate family efflux transporterRHOM_RS01145Not AvailablePositive269837 - 27104843513.6
hypothetical proteinRHOM_RS17540Not AvailablePositive271153 - 2712935257.16
hypothetical proteinRHOM_RS18275Not AvailablePositive271256 - 27206929555.6
lysr family transcriptional regulatorRHOM_RS01155Not AvailableNegative272081 - 27296532817.6
yoak family proteinRHOM_RS01160Not AvailablePositive273156 - 27381224641.6
duf4866 domain-containing proteinRHOM_RS01165Not AvailablePositive273838 - 27463831112.2
fusc family proteinRHOM_RS01170Not AvailablePositive274654 - 27596149590.9
adenylosuccinate synthaseRHOM_RS01175Not AvailablePositive275979 - 27727147296.7

Displaying genes 231 – 240 of 3351 in total

Metabolites

388 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da

Displaying 1–10 of 388 metabolites

Health Effects

No health effects information available for this bacterium.