Prevotella melaninogenica ATCC 25845

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Prevotellaceae

Genus

Prevotella

Description

Prevotella melaninogenica ATCC 25845 is a mesophilic, Gram-negative, rod-shaped bacterium that belongs to the family Prevotellaceae. As a chemoheterotroph, it derives its energy from the breakdown of organic compounds, utilizing a variety of carbon sources as its energy source. This bacterium is capable of producing energy through the process of fermentation, where it converts glucose and other sugars into lactate, ethanol, and carbon dioxide. P. melaninogenica ATCC 25845 is classified as a facultative anaerobe, meaning it can grow in both aerobic and anaerobic environments. It exhibits a growth preference for microaerobic conditions, where oxygen levels are moderate, making it thrive in areas with limited oxygen availability. Its cell shape is characterized by a rod-like morphology, with dimensions ranging from 0.5-1.5 μm in width and 2-5 μm in length. P. melaninogenica ATCC 25845 is commonly found in the oral cavity, respiratory tract, and gastrointestinal tract of humans, as well as in soil and sediments. The bacterium's metabolic capabilities are supplemented by its ability to produce melanin, a pigment produced through the oxidation of tyrosine. This unique characteristic allows it to thrive in environments with high levels of tyrosine, such as those found in soil and decaying matter. In addition to its vital functions in the ecosystem, P. melaninogenica ATCC 25845 has earned recognition for its potential role in human health. Research has indicated that this microbe is involved in the breakdown of complex lipids and the production of bioactive compounds, which may have therapeutic applications. Furthermore, studies have suggested that alterations in the gut microbiome, including changes in the presence of P. melaninogenica ATCC 25845, may be associated with various human diseases, such as inflammatory bowel disease and colon cancer.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPrevotellaceae
GenusPrevotella
SpeciesPrevotella melaninogenica
StrainATCC 25845

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Prevotella melaninogenica ATCC 25845
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Prevotella melaninogenica ATCC 25845


Gene Summary

Adenine Count

527299 bp

Thymine Count

534017 bp

Guanine Count

368315 bp

Cytosine Count

366777 bp

Genome Length

1796408 bp

Protein-coding Genes

1385 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chromosomal replication initiator protein dnaaHMPREF0659_RS07135Not AvailablePositive199 - 160553378.0
hypothetical proteinHMPREF0659_RS12810Not AvailablePositive2410 - 25505071.43
na+/h+ antiporterHMPREF0659_RS07140Not AvailablePositive2719 - 432359974.5
iron-containing alcohol dehydrogenaseHMPREF0659_RS07145Not AvailableNegative4852 - 601842946.9
carboxymuconolactone decarboxylase family proteinHMPREF0659_RS07150Not AvailableNegative6042 - 683029627.9
is4 family transposaseHMPREF0659_RS07155Not AvailablePositive7133 - 745012505.3
is4 family transposaseHMPREF0659_RS07165Not AvailableNegative9265 - 94687625.52
gh-e family nucleaseHMPREF0659_RS07170Not AvailablePositive9612 - 97977455.91
ankyrin repeat domain-containing proteinHMPREF0659_RS07175Not AvailablePositive9810 - 1028917967.1
hypothetical proteinHMPREF0659_RS13035Not AvailablePositive10511 - 105642056.52

Displaying genes 1 – 10 of 2452 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PeriodontitisCausesPMC1681585
PneumoniaCausesPMC1681585

Displaying health effects 1 – 2 of 2 in total