Actinomyces oris

Gram-positiveFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Actinomyces

Description

Actinomyces oris is a gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, categorizing it as a chemoheterotroph, and can be found in various body sites, including the oral cavity, gut, and urogenital tract, in all possible species of humans. As an obligate anaerobe, A. oris requires the absence of oxygen to grow and survive.The gram-positive characteristic of A. oris indicates the presence of a thick peptidoglycan layer in its cell wall, which retains the crystal violet stain used in the gram-staining procedure, appearing purple under a microscope. The rod shape of A. oris allows it to inhabit and interact with its environment in a specific way, often forming colonies and biofilms.As a chemoheterotroph, A. oris relies on organic compounds for energy and carbon, breaking down complex molecules into simpler ones to sustain its metabolic processes. This is evident in its ability to degrade a variety of substrates, including carbohydrates and proteins.The mesophilic temperature preference of A. oris allows it to thrive in temperatures ranging from 20-45°C, which is typical of the human body's temperature. This adaptability enables A. oris to colonize various body sites, including those with limited oxygen availability.A. oris plays a significant role in the human oral microbiome, contributing to the formation of dental plaque and influencing the overall health of the oral cavity. The presence of A. oris has been linked to periodontal diseases, highlighting the importance of understanding its interactions with the host and other microorganisms.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusActinomyces
SpeciesActinomyces oris
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Actinomyces oris
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatsubmucosal sulcus; vaginal mucosa
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

479441 bp

Thymine Count

480348 bp

Guanine Count

1040040 bp

Cytosine Count

1043088 bp

Genome Length

3042917 bp

Protein-coding Genes

2468 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

7

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
nicotinate-nucleotide adenylyltransferaseAXE84_RS00010Not Available-698 - 138125103.0
rok family proteinAXE84_RS00015Not Available-1560 - 265137127.8
deor/glpr family dna-binding transcription regulatorAXE84_RS00020Not Available+2936 - 371227206.6
glycosyltransferase family proteinAXE84_RS00025Not Available+3825 - 511746886.1
glycosyltransferaseAXE84_RS00030Not Available+5114 - 640046472.6
glycosyltransferase family 4 proteinAXE84_RS00035Not Available+6400 - 756941664.7
abc transporter atp-binding proteinAXE84_RS00040Not Available+7620 - 939562663.9
aminoglycoside phosphotransferase family proteinAXE84_RS00045Not Available+9392 - 1060943552.2
phosphotransferaseAXE84_RS00050Not Available+10642 - 1170339012.7
udp-glucose/gdp-mannose dehydrogenase family proteinAXE84_RS00055Not Available+11700 - 1302546541.4

Displaying genes 1 – 10 of 17764 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

233 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0002197D-arabinoseC5H10O5Chemical structure of D-arabinoseNot available
Average150.1299Da
Monoisotopic150.05282343Da
BASm00022412-demethylmenaquinone-8C50H70O2Chemical structure of 2-demethylmenaquinone-8Not available
Average703.0896Da
Monoisotopic702.5375815Da

Displaying 1–10 of 233 metabolites