Bifidobacterium bifidum BGN4

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

The microbe Bifidobacterium bifidum BGN4 exhibits the following characteristics: Thermophilic (-phile), Chemoheterotroph, using oxidative phosphorylation for energy production, Gram-positive, banana-shaped, present in the gastrointestinal tract of humans and animals, and has an Obligate Anaerobe oxygen preference. As a Thermophilic microbe, Bifidobacterium bifidum BGN4 thrives in high-temperature environments, typically between 37°C to 45°C. This adaptation allows it to inhabit the human gut, where the temperature is stable and favorable for its growth. As a Chemoheterotroph, Bifidobacterium bifidum BGN4 uses organic compounds as its energy source, typically in the form of carbohydrates, peptides, and fats. It obtains these compounds from its host's diet or from the breakdown of host tissues. The microbe produces energy through oxidative phosphorylation, where energy from the breakdown of molecules is used to generate ATP. Bifidobacterium bifidum BGN4 is a Gram-positive microbe, characterized by the presence of a thick peptidoglycan layer in its cell wall. This layer provides structural support and helps maintain the cell's shape, which is typically banana-shaped. Bifidobacterium bifidum BGN4 is found in the gastrointestinal tract of humans and animals, where it plays a crucial role in the breakdown and absorption of nutrients. It is also present in fermented foods and supplements, where it is used as a probiotic. As an Obligate Anaerobe, Bifidobacterium bifidum BGN4 requires a strictly anaerobic environment to grow. This means that it cannot tolerate the presence of oxygen, which can be toxic to the microbe. Instead, it thrives in environments where oxygen levels are low or absent. Bifidobacterium bifidum BGN4 has been shown to have a range of beneficial effects on human health, including the regulation of gut motility, inflammation, and immune responses. It has also been used as a probiotic in the treatment of various gastrointestinal disorders, such as irritable bowel syndrome and inflammatory bowel disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium bifidum
StrainBGN4

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium bifidum BGN4
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium bifidum BGN4, complete sequence.

Gene Summary

Adenine Count

414870 bp

Thymine Count

415708 bp

Guanine Count

696144 bp

Cytosine Count

696942 bp

Genome Length

2223664 bp

Protein-coding Genes

1781 genes

Non-Coding Genes

73 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type i dna topoisomeraseBBB_RS08610Not AvailableNegative2062521 - 2065439104648.0
phosphatase pap2 family proteinBBB_RS08615Not AvailableNegative2065524 - 206692148535.5
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive2067175 - 2067269Not Available
s8 family serine peptidaseBBB_RS08620Not AvailableNegative2067361 - 2071428140104.0
paqr family membrane homeostasis protein trhaBBB_RS08625Not AvailablePositive2071953 - 207286131945.6
udp-galactopyranose mutaseBBB_RS08630Not AvailablePositive2073071 - 207423744532.0
transglycosylase domain-containing proteinBBB_RS08635Not AvailablePositive2074697 - 207719586437.6
2-isopropylmalate synthaseBBB_RS08640Not AvailableNegative2077364 - 207927470303.5
metallophosphoesterase family proteinBBB_RS08645Not AvailablePositive2079766 - 208116651421.3
hypothetical proteinBBB_RS08650Not AvailableNegative2081350 - 20815145585.65

Displaying genes 1741 – 1750 of 1854 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

351 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 351 metabolites

Health Effects

No health effects information available for this bacterium.