Roseburia inulinivorans

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia inulinivorans is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, classified as a chemoheterotroph, and can be found in various body sites of humans and animals, including the gut, skin, and mucous membranes. As an obligate anaerobe, it requires a strict anaerobic environment to survive, which is typically found in the gastrointestinal tract. The Gram-positive characteristic indicates that the microbe has a thick peptidoglycan layer in its cell wall, providing structural support and protection. Its rod-shaped morphology allows it to maintain a large surface area, facilitating the uptake of nutrients from its surroundings. As a chemoheterotroph, Roseburia inulinivorans relies on organic compounds for energy and carbon, breaking down complex molecules such as inulin, a polysaccharide found in plants. This ability to degrade inulin allows the microbe to thrive in environments where other microbes may struggle to survive. The mesophilic temperature preference of Roseburia inulinivorans allows it to grow optimally at temperatures between 20-45°C, making it well-suited to the temperatures found in the human gut. Roseburia inulinivorans plays a significant role in the human gut microbiome, contributing to the breakdown of complex carbohydrates and producing short-chain fatty acids, which provide energy to the host. Its presence has been linked to various health benefits, including the regulation of the immune system and the maintenance of a healthy gut barrier. The microbe's ability to produce butyrate, a short-chain fatty acid, has also been shown to have anti-inflammatory properties, highlighting its potential importance in the prevention and treatment of certain diseases.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia inulinivorans
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Roseburia inulinivorans
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Roseburia inulinivorans strain AM27-11 AM27-11.Scaf100, whole

Gene Summary

Adenine Count

1150198 bp

Thymine Count

1156374 bp

Guanine Count

808755 bp

Cytosine Count

819648 bp

Genome Length

3936388 bp

Protein-coding Genes

3531 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ylbf family regulatorDW707_16050Not AvailableNegative3423244 - 342358813467.9
ribonuclease jDW707_16055Not AvailableNegative3423620 - 342528761235.2
duf1292 domain-containing proteinDW707_16060Not AvailableNegative3425595 - 34258529835.27
holliday junction resolvase ruvxDW707_16065Not AvailableNegative3425915 - 342635216894.5
ireb family regulatory phosphoproteinDW707_16070Not AvailableNegative3426444 - 342670710200.2
trna (n(6)-l-threonylcarbamoyladenosine(37)-c(2))- methylthiotransferase mtabDW707_16075Not AvailableNegative3426819 - 342813550204.1
hpr family phosphocarrier proteinDW707_16080Not AvailablePositive3428223 - 34284538598.53
trna 4-thiouridine(8) synthase thiiDW707_16085Not AvailableNegative3428550 - 342973144260.7
cysteine desulfuraseDW707_16090Not AvailableNegative3429808 - 343097742704.4
16s rrna (uracil(1498)-n(3))-methyltransferaseDW707_16095Not AvailableNegative3431012 - 343176728250.2

Displaying genes 3091 – 3100 of 14074 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

44 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014031Butyric acidC4H8O2Chemical structure of Butyric acid107-92-6
Average88.1051Da
Monoisotopic88.0524295Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014040Indoleacetic acidC10H9NO2Chemical structure of Indoleacetic acid87-51-4
Average175.184Da
Monoisotopic175.063328537Da
BASm0014043Phenylacetic acidC8H8O2Chemical structure of Phenylacetic acid103-82-2
Average136.1479Da
Monoisotopic136.0524295Da
BASm0014064Arachidonic acidC20H32O2Chemical structure of Arachidonic acid506-32-1
Average304.4669Da
Monoisotopic304.240230268Da
BASm0014068Nicotinic acidC6H5NO2Chemical structure of Nicotinic acid59-67-6
Average123.1094Da
Monoisotopic123.032028409Da
BASm0014085AmylopectinC30H52O26Chemical structure of Amylopectin9037-22-3
Average828.7183Da
Monoisotopic828.274681836Da
BASm0014097Gentisic acidC7H6O4Chemical structure of Gentisic acidNULL
Average154.121Da
Monoisotopic154.026608673Da
BASm0014102cis-4-Hydroxycyclohexylacetic acidC8H14O3Chemical structure of cis-4-Hydroxycyclohexylacetic acidNULL
Average158.195Da
Monoisotopic158.094294314Da
BASm0014108Erythronic acidC4H8O5Chemical structure of Erythronic acidNULL
Average136.1033Da
Monoisotopic136.037173366Da

Displaying 1–10 of 44 metabolites

Health Effects

No health effects information available for this bacterium.