Roseburia hominis

Gram-negativeRodAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Roseburia

Description

Roseburia hominis is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, classified as a Chemoheterotroph, and can be found in various body sites, including the gut, skin, and mucous membranes, across different species. As an Obligate Anaerobe, it requires a strict anaerobic environment to survive, which is reflected in its ability to flourish in low-oxygen conditions. The Gram-positive characteristic of R. hominis indicates the presence of a thick peptidoglycan layer in its cell wall, providing structural support and shape to the microbe. Its rod-shaped morphology allows for efficient absorption of nutrients and interaction with its environment. As a Chemoheterotroph, R. hominis relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its metabolic processes. This characteristic enables the microbe to inhabit a wide range of environments, from the human gut to soil and sediment. The mesophilic temperature preference of R. hominis allows it to thrive in temperatures between 20-45°C, making it well-suited to the conditions found in the human body. Its ability to inhabit various body sites, including those with limited oxygen availability, highlights its adaptability and resilience. R. hominis plays a crucial role in the degradation of complex polysaccharides and production of short-chain fatty acids, which can influence the host's immune system and overall health. Notably, research has shown that R. hominis is capable of producing butyrate, a key metabolite with anti-inflammatory properties, which may have implications for the treatment of various diseases, including inflammatory bowel disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusRoseburia
SpeciesRoseburia hominis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Roseburia hominis
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatintestinal microbiome
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

CYZJ00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

90 genes

Non-Coding Genes

11 genes

# of Chromosomes/Plasmids

1

Genes

No genes available for this genome.

Pathways

22 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

107 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0014031Butyric acidC4H8O2Chemical structure of Butyric acid107-92-6
Average88.1051Da
Monoisotopic88.0524295Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014040Indoleacetic acidC10H9NO2Chemical structure of Indoleacetic acid87-51-4
Average175.184Da
Monoisotopic175.063328537Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da

Displaying 1–10 of 107 metabolites

Health Effects

No health effects information available for this bacterium.