Cronobacter sakazakii ATCC BAA-894

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Cronobacter

Description

Cronobacter sakazakii ATCC BAA-894 is a gram-negative, rod-shaped bacterium that thrives in mesophilic conditions, showing a temperature preference of around 30-37°C. As a chemoheterotroph, it relies on organic compounds for energy and carbon, making it adaptable to various environments. This bacterium is classified as a facultative anaerobe, allowing it to grow in the presence or absence of oxygen, although it prefers aerobic conditions. Cronobacter sakazakii is known for its presence in various environments, notably in dried foods such as powdered infant formula and other food products. Its versatility allows it to inhabit not only food sources but also environmental niches like soil and water. The ability to survive desiccation and resist harsh conditions makes it a significant concern for food safety. This pathogen can colonize the gastrointestinal tract, and its implications are particularly severe in neonates and immunocompromised individuals, leading to conditions like meningitis and enteritis. In terms of pathogenicity, Cronobacter sakazakii has been associated with severe infections, especially in infants, where it may cause necrotizing enterocolitis. It can produce biofilms, contributing to its persistence in food-processing environments, complicating efforts at decontamination. Furthermore, this microbe exhibits resistance to multiple antibiotics, raising concerns in clinical settings regarding treatment efficacy. In addition to its health implications, research has demonstrated that Cronobacter sakazakii possesses unique biochemical properties that allow for the production of various enzymes, leading to potential applications in biotechnology. The ongoing study of this bacterium continues to shed light on its role in food safety and human health, making it a subject of great scientific interest.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCronobacter
SpeciesCronobacter sakazakii
StrainATCC BAA-895

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cronobacter sakazakii ATCC BAA-894
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Cronobacter sakazakii ATCC BAA-894 plasmid pESA3, complete

Gene Summary

Adenine Count

28065 bp

Thymine Count

28548 bp

Guanine Count

37739 bp

Cytosine Count

36844 bp

Genome Length

131196 bp

Protein-coding Genes

116 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
regulatory protein ycgzESA_RS20790Not AvailableNegative27137 - 273768983.87
diguanylate phosphodiesteraseESA_RS20795Not AvailablePositive27777 - 2899444893.9
merr family transcriptional regulatorESA_RS20800Not AvailablePositive29229 - 2997228181.0
methyl-accepting chemotaxis proteinESA_RS20805Not AvailableNegative30051 - 3196167280.6
hypothetical proteinESA_RS20810Not AvailablePositive32394 - 3278014927.7
gnat family n-acetyltransferaseESA_RS20815Not AvailableNegative32818 - 3322814958.0
antibiotic biosynthesis monooxygenase family proteinESA_RS20820Not AvailablePositive33435 - 3375812251.5
amino acid-binding proteinESA_RS20825Not AvailablePositive33751 - 3414914162.9
arsr/smtb family transcription factorESA_RS20830Not AvailablePositive34122 - 3484725955.3
alpha/beta fold hydrolaseESA_RS20835Not AvailablePositive34929 - 3575029807.0

Displaying genes 31 – 40 of 4325 in total

Metabolites

2229 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da

Displaying 1–10 of 2229 metabolites

Health Effects

No health effects information available for this bacterium.