Cronobacter sakazakii ATCC BAA-894

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Cronobacter

Description

Cronobacter sakazakii ATCC BAA-894 is a gram-negative, rod-shaped bacterium that thrives in mesophilic conditions, showing a temperature preference of around 30-37°C. As a chemoheterotroph, it relies on organic compounds for energy and carbon, making it adaptable to various environments. This bacterium is classified as a facultative anaerobe, allowing it to grow in the presence or absence of oxygen, although it prefers aerobic conditions. Cronobacter sakazakii is known for its presence in various environments, notably in dried foods such as powdered infant formula and other food products. Its versatility allows it to inhabit not only food sources but also environmental niches like soil and water. The ability to survive desiccation and resist harsh conditions makes it a significant concern for food safety. This pathogen can colonize the gastrointestinal tract, and its implications are particularly severe in neonates and immunocompromised individuals, leading to conditions like meningitis and enteritis. In terms of pathogenicity, Cronobacter sakazakii has been associated with severe infections, especially in infants, where it may cause necrotizing enterocolitis. It can produce biofilms, contributing to its persistence in food-processing environments, complicating efforts at decontamination. Furthermore, this microbe exhibits resistance to multiple antibiotics, raising concerns in clinical settings regarding treatment efficacy. In addition to its health implications, research has demonstrated that Cronobacter sakazakii possesses unique biochemical properties that allow for the production of various enzymes, leading to potential applications in biotechnology. The ongoing study of this bacterium continues to shed light on its role in food safety and human health, making it a subject of great scientific interest.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusCronobacter
SpeciesCronobacter sakazakii
StrainATCC BAA-895

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Cronobacter sakazakii ATCC BAA-894
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Cronobacter sakazakii ATCC BAA-894 plasmid pESA2, complete

Gene Summary

Adenine Count

7903 bp

Thymine Count

7207 bp

Guanine Count

7957 bp

Cytosine Count

8141 bp

Genome Length

31208 bp

Protein-coding Genes

36 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidine phosphatase family proteinESA_RS20640Not AvailablePositive957 - 157422384.5
membrane proteinESA_RS20645Not AvailablePositive1673 - 244027366.5
parb/srx family n-terminal domain-containing proteinESA_RS20650Not AvailablePositive2564 - 362240571.0
gnat family n-acetyltransferaseESA_RS20655Not AvailableNegative3627 - 415720027.5
mfs transporterESA_RS20660Not AvailablePositive4454 - 566242288.3
omptin family outer membrane protease cpaESA_RS20665Not AvailablePositive5978 - 691635095.5
carbapenem self-resistance protein carg family proteinESA_RS20670Not AvailablePositive7165 - 770719820.1
hypothetical proteinESA_RS20675Not AvailablePositive7704 - 824320018.4
helix-turn-helix transcriptional regulatorESA_RS20680Not AvailablePositive8276 - 897126377.1
voc family proteinESA_RS20685Not AvailablePositive9028 - 941114570.5

Displaying genes 1 – 10 of 4325 in total

Metabolites

1782 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1782 metabolites

Health Effects

No health effects information available for this bacterium.