Clostridium perfringens SM101

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium perfringens SM101 is a Gram-positive, rod-shaped bacterium that thrives in anaerobic conditions, making it an obligate anaerobe. This microbe prefers a temperature range of 30-37°C, classifying it as mesophilic. C. perfringens SM101 is a heterotroph, relying on organic compounds as a source of carbon and energy for growth, which occurs primarily in oxygen-deprived environments like the intestines of humans and animals, soil, and decaying organic matter. As an obligate anaerobe, C. perfringens SM101 cannot survive in the presence of oxygen, and its metabolic processes are adapted to utilize fermentation pathways. This bacterium's ability to produce various enzymes allows it to break down proteins, sugars, and complex carbohydrates, facilitating its survival in environments where competing microorganisms might struggle. The organism is commonly associated with foodborne illnesses, particularly in improperly stored meats, as it can multiply rapidly and produce potent toxins that lead to conditions such as gas gangrene, and enterotoxemia. In addition to its pathogenic potential, C. perfringens SM101 is noteworthy for its role in industrial applications, such as waste treatment and bioremediation, where its robust enzymatic activity can assist in the breakdown of organic pollutants. This microbe also serves as a model organism in research settings, aiding scientists in understanding anaerobic metabolism and the complexities of microbial interactions in ecosystems.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium perfringens
StrainSM101

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium perfringens SM101
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles - Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Clostridium perfringens SM101 plasmid pSM101A, complete sequence.

Gene Summary

Adenine Count

4955 bp

Thymine Count

4134 bp

Guanine Count

2123 bp

Cytosine Count

1185 bp

Genome Length

12397 bp

Protein-coding Genes

11 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
yihy/virulence factor brkb family proteinCPR_RS01460Not AvailablePositive330756 - 33160732300.9
udp-glucose 4-epimerase galeCPR_RS01465Not AvailableNegative331668 - 33265436358.4
single-stranded dna-binding proteinCPR_RS01470Not AvailablePositive332808 - 33315213282.1
fpra family a-type flavoproteinCPR_RS01475Not AvailableNegative333227 - 33442644689.8
23s rrna (pseudouridine(1915)-n(3))-methyltransferase rlmhCPR_RS13890Not AvailableNegative334905 - 33579432246.7
rna-guided endonuclease insq/tnpb family proteinCPR_RS01485Not AvailableNegative335925 - 33711546325.6
23s rrna (pseudouridine(1915)-n(3))-methyltransferase rlmhCPR_RS01490Not AvailableNegative337524 - 34006094746.9
duf6514 family proteinCPR_RS01495Not AvailablePositive340430 - 34073511707.2
holo-acp synthaseCPR_RS01500Not AvailablePositive340784 - 34118514768.8
bifunctional adp-dependent nad(p)h-hydrate dehydratase/nad(p)h-hydrate epimeraseCPR_RS01505Not AvailablePositive341172 - 34267154970.4

Displaying genes 311 – 320 of 2711 in total

Metabolites

1634 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001808corynebactinC39H42N6O18Chemical structure of corynebactinNot available
Average882.789Da
Monoisotopic882.2555585Da
BASm0001861(2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diolC12H12O2Chemical structure of (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diolNot available
Average188.226Da
Monoisotopic188.0837296Da

Displaying 1–10 of 1634 metabolites

Health Effects

No health effects information available for this bacterium.