Clostridioides difficile 630

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Peptostreptococcales

Family

Peptostreptococcaceae

Genus

Clostridioides

Description

Clostridioides difficile 630 is a gram-positive, rod-shaped bacterium that thrives in anaerobic environments, characterized by its temperature preference for mesophilic conditions, within the range of 25-40°C. As a chemoheterotroph, it obtains its energy by breaking down organic compounds, specifically glycans, peptides, and proteins, in the absence of light. This microbe is an obligate anaerobe, requiring a low oxygen environment to survive, which is typical of many Clostridium species. Upon staining, C. difficile 630 exhibits a characteristic Gram-positive reaction, indicating a thick peptidoglycan layer in its cell wall. Its rod-shaped morphology, also known as a bacillus, is a defining feature of the genus Clostridium. In terms of its habitat, C. difficile 630 can be found colonizing the gastrointestinal tract of humans and animals, as well as other body sites, including the skin, respiratory tract, and genitourinary tract. This microbe's ability to produce energy is attributed to its fermentation process, where it converts glucose into lactate, acetate, and other short-chain fatty acids. This process is anaerobic, occurring in the absence of oxygen, which is typical of many anaerobic microbes. Despite its ability to thrive in anaerobic environments, C. difficile 630 has been linked to severe infections in humans, particularly in healthcare settings. The microbe's ability to adhere to epithelial cells and produce potent toxins, A and B, contributes to its pathogenic potential. Furthermore, the development of antibiotic resistance in C. difficile 630 has made treatment challenging, highlighting the importance of continued research and infection control measures. In addition to its importance in human health, C. difficile 630 has also been used as a model organism in research studies, particularly in the fields of microbiology, immunology, and infectious disease. Its ability to colonize the gastrointestinal tract and produce toxins has made it an important tool for studying the interactions between microbes and the host immune system.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderPeptostreptococcales
FamilyPeptostreptococcaceae
GenusClostridioides
SpeciesClostridioides difficile
Strain630

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridioides difficile 630
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs-Singles-Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Clostridioides difficile 630


Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

8 genes

Non-Coding Genes

1 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinCD630_RS19580Not AvailableNegative1 - 45617343.3
dead/deah box helicaseCD630_RS19585Not AvailableNegative593 - 3202100654.0
hypothetical proteinCD630_RS19590Not AvailableNegative3464 - 378412727.3
ribbon-helix-helix domain-containing proteinCD630_RS19595Not AvailablePositive3928 - 40775822.18
hypothetical proteinCD630_RS19600Not AvailablePositive4150 - 469521083.9
hypothetical proteinCD630_RS19605Not AvailableNegative4878 - 50787388.84
hnh endonucleaseCD630_RS19610Not AvailableNegative5236 - 552911194.6
hypothetical proteinCD630_RS19615Not AvailableNegative5529 - 57448297.17
phage major capsid proteinCD630_RS19620Not AvailableNegative5996 - 732749371.6
AttlNot AvailableNot AvailablePositive1088107 - 1088126Not Available

Displaying genes 1 – 10 of 3981 in total

Metabolites

114 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001691hydrogenselenideHSeChemical structure of hydrogenselenideNot available
Average79.98Da
Monoisotopic80.924896Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–10 of 114 metabolites

Health Effects

No health effects information available for this bacterium.