Cupriavidus metallidurans CH34

Gram-negativeRodMotileFacultative

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Cupriavidus

Description

Cupriavidus metallidurans CH34. This strain was first identified in the heavy metal-contaminated sludge of a settling tank in Belgium in the late 1970s. Metal resistance functions are predominantly encoded on two plasmids, pMOL28 and pMOL30, which produce metal exporters that pump metal ions out of the cell, thus protecting intracellular macromolecules from the toxic effects of high concentrations of metal. (NCBI BioProject: bp_list[1])

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Betaproteobacteria
Order	Burkholderiales
Family	Burkholderiaceae
Genus	Cupriavidus
Species	Cupriavidus metallidurans
Strain	CH34

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	Not Available

AI-generated image based on bacteria physiology

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	Specialized
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Not Available

Genome Summary

Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence.

NC_007972.2 NC_007974.2 NC_007971.2 NC_007973.1

Gene Summary

Adenine Count

34395 bp

Thymine Count

33323 bp

Guanine Count

51333 bp

Cytosine Count

52408 bp

Genome Length

171459 bp

Protein-coding Genes

168 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
pas domain-containing sensor histidine kinase	RMET_RS23255	Not Available	Positive	1120203 - 1121354	42267.0
response regulator transcription factor	RMET_RS23260	Not Available	Positive	1121351 - 1121995	23680.8
universal stress protein	RMET_RS23265	Not Available	Negative	1122026 - 1122478	15686.1
universal stress protein	RMET_RS23270	Not Available	Positive	1122677 - 1123525	30244.0
mbl fold metallo-hydrolase rna specificity domain-containing protein	RMET_RS23275	Not Available	Negative	1123601 - 1124959	50027.2
universal stress protein	RMET_RS23280	Not Available	Negative	1125064 - 1125888	28732.7
helix-turn-helix domain-containing protein	RMET_RS23285	Not Available	Positive	1126289 - 1127062	28750.5
glxa family transcriptional regulator	RMET_RS23290	Not Available	Negative	1127083 - 1128024	34350.3
sdr family nad(p)-dependent oxidoreductase	RMET_RS23295	Not Available	Positive	1128168 - 1128968	28449.2
fmn-binding negative transcriptional regulator	RMET_RS23300	Not Available	Negative	1129002 - 1129652	24074.6

Displaying genes 1201 – 1210 of 6407 in total

Pathways

1469 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Lysine Biosynthesis

Taurine Metabolism

TCA Cycle

Glycolysis and Pyruvate Dehydrogenase

Arginine Metabolism

Ornithine Metabolism

Show All 1469 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000250	2,5-didehydro-D-gluconateC6H7O7	`53736-12-2`	Average191.1156Da Monoisotopic191.019177578Da
BASm0000253	2-oxopent-4-enoateC5H5O3	Not available	Average113.093Da Monoisotopic113.024417601Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000516	6-deoxyerythronolide BC21H38O6	Not available	Average386.5228Da Monoisotopic386.2668389Da
BASm0000553	biphenyl-2,3-diolC12H10O2	Not available	Average186.2066Da Monoisotopic186.0680796Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da
BASm0000599	2,5-dihydroxypyridineC5H5NO2	Not available	Average111.1Da Monoisotopic111.0320284Da
BASm0000893	crotonobetaineC7H13NO2	`927-89-9`	Average143.1836Da Monoisotopic143.0946287Da
BASm0000989	GlycerolC3H8O3	`56-81-5`	Average92.0938Da Monoisotopic92.04734412Da

Displaying 1–10 of 1772 metabolites

Health Effects

No health effects information available for this bacterium.