Clostridium perfringens str. 13

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium perfringens str. 13 is a Gram-positive, rod-shaped bacterium that thrives in anaerobic environments, demonstrating a preference for mesophilic temperatures, making it active between 20°C and 45°C. As a heterotroph, it obtains its nutrients by decomposing organic matter, primarily carbohydrates and proteins. This microbe is predominantly found in the gastrointestinal tracts of various animals, including humans, and can also inhabit soil, sediments, and decaying organic material. The Gram-positive nature of C. perfringens str. 13 is characterized by a thick peptidoglycan layer in its cell wall, which contributes to its resilience in harsh conditions. Its rod-like shape allows for efficient movement and colonization in nutrient-rich environments, making it capable of rapid growth under suitable conditions. As a mesophilic organism, it adapts well to body temperatures, which is particularly significant for its role in human and animal health. C. perfringens str. 13 is classified as an obligate anaerobe, meaning it cannot survive in the presence of oxygen. This characteristic is crucial for its pathogenicity, as it thrives in the anaerobic environments of deep tissue infections, such as gas gangrene, where it produces potent toxins. Its heterotrophic metabolism enables it to efficiently utilize the nutrients available in host tissues. In addition to its role in human disease, Clostridium perfringens is also notable for its ability to produce spores that can survive extreme environmental conditions. These spores can lead to foodborne illness, particularly in improperly cooked meats, emphasizing the importance of food safety practices. The microbe's diverse metabolic capabilities and ecological versatility underline its significance in both health and environmental contexts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium perfringens
Strain13

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium perfringens str. 13
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementSingles - Pairs - Chains
SporulationSporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Clostridium perfringens str. 13 plasmid pCP13, complete sequence.

Gene Summary

Adenine Count

19177 bp

Thymine Count

21286 bp

Guanine Count

6196 bp

Cytosine Count

7651 bp

Genome Length

54310 bp

Protein-coding Genes

57 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AntirepressorCPE_RS05885Not AvailablePositive1310119 - 131121642846.5
hypothetical proteinCPE_RS05890Not AvailablePositive1311383 - 131164910671.2
hypothetical proteinCPE_RS05895Not AvailablePositive1311688 - 131207114241.9
Hypothetical proteinCPE_RS05900Not AvailablePositive1312073 - 13122526617.69
hypothetical proteinCPE_RS05905Not AvailablePositive1312258 - 13125009655.83
Hnh endonuclease family proteinCPE_RS05910Not AvailablePositive1312560 - 131297016626.3
Terminase small subunitCPE_RS05915Not AvailablePositive1313082 - 131356718039.9
Terminase large subunitCPE_RS05920Not AvailablePositive1313567 - 131524365096.5
Putative portal proteinCPE_RS05925Not AvailablePositive1315442 - 131666545468.6
Putative prohead proteaseCPE_RS05930Not AvailablePositive1316640 - 131724222939.0

Displaying genes 1 – 10 of 2830 in total

Metabolites

1670 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 1670 metabolites

Health Effects

No health effects information available for this bacterium.