Dorea longicatena

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea longicatena is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, classified as a chemoheterotroph, which obtains its energy by breaking down organic compounds, and can be found in various body sites across different species, including the human gut, and is an obligate anaerobe, requiring the absence of oxygen to survive. The Gram-positive characteristic indicates that the microbe has a thick peptidoglycan layer in its cell wall, providing it with a robust defense mechanism. Its rod shape allows for efficient movement and colonization in its environment. As a mesophile, Dorea longicatena grows best in moderate temperatures, typically between 20-45°C, making it well-suited for the human gut, where temperatures are relatively stable.As a chemoheterotroph, Dorea longicatena relies on the breakdown of organic compounds to produce energy, using enzymes to catalyze the reactions. This process allows the microbe to thrive in environments with abundant organic matter, such as the human gut, where it can feed on undigested carbohydrates and other nutrients. The absence of oxygen is crucial for the microbe's survival, as it is an obligate anaerobe, and even small amounts of oxygen can be detrimental to its growth.Dorea longicatena plays a significant role in the human gut microbiome, contributing to the breakdown of complex carbohydrates and producing short-chain fatty acids, which provide energy to the host. Its presence has also been linked to various health benefits, including the regulation of the immune system and the maintenance of a healthy gut barrier. The unique characteristics of Dorea longicatena make it an essential component of the human gut microbiome, and its study has shed light on the complex interactions between microbes and their hosts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea longicatena
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

2837 genes

Non-Coding Genes

187 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Site-specific recombinaseDW690_16900Not AvailableNegative3637392 - 363901462139.9
AttlNot AvailableNot AvailablePositive3639097 - 3639110Not Available
hypothetical proteinDW690_16905Not AvailableNegative3639144 - 36393416947.32
Atp-binding proteinDW690_16910Not AvailableNegative3639338 - 364019233021.3
Dna replication proteinDW690_16915Not AvailableNegative3640255 - 364101928861.4
hypothetical proteinDW690_16920Not AvailableNegative3641121 - 364150714925.0
relaxaseDW690_16925Not AvailableNegative3641497 - 364312861880.1
plasmid mobilization relaxosome protein mobcDW690_16930Not AvailableNegative3643100 - 364349514602.6
CbDW690_16935Not AvailableNegative3644435 - 364487516270.5
hypothetical proteinDW690_16940Not AvailablePositive3645308 - 36454967297.26

Displaying genes 1 – 10 of 8354 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

7 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00032855-methyltetrahydropteroyltri-L-glutamateC30H35N9O12Chemical structure of 5-methyltetrahydropteroyltri-L-glutamateNot available
Average713.663Da
Monoisotopic713.2427119Da
BASm0003333(2R)-3-phosphoglycerateC3H4O7PChemical structure of (2R)-3-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003346(2R)-2-phosphoglycerateC3H4O7PChemical structure of (2R)-2-phosphoglycerateNot available
Average183.033Da
Monoisotopic182.9711102Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm00034561-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamideC15H21N5O15P2Chemical structure of 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamideNot available
Average573.2993Da
Monoisotopic573.0509381Da
BASm00035255-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamideC15H21N5O15P2Chemical structure of 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamideNot available
Average573.303Da
Monoisotopic573.0531333Da

Displaying 1–7 of 7 metabolites

Health Effects

No health effects information available for this bacterium.