Rothia mucilaginosa

Gram-positiveCocciMotileMicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Micrococcaceae

Genus

Rothia

Description

Rothia mucilaginosa is a gram-positive, coccoid-shaped microbe that thrives in mesophilic temperatures, classified as a chemoheterotroph, and can be found in various body sites, including the skin, respiratory tract, and gastrointestinal tract, of humans and other species. As a chemoheterotroph, R. mucilaginosa relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its growth. Its gram-positive cell wall and coccoid shape allow it to maintain its structure and withstand environmental stresses. The microbe's mesophilic temperature preference enables it to adapt to a wide range of environments, from the human body to various ecological niches. As a facultative anaerobe, R. mucilaginosa can survive in both oxygen-rich and oxygen-poor conditions, making it a versatile microorganism. Its ability to colonize different body sites in various species highlights its adaptability and capacity to coexist with diverse host organisms. Notably, R. mucilaginosa has been implicated in oral and respiratory infections, and its role in the human microbiome is still being explored, with recent studies suggesting that it may play a role in the breakdown of complex sugars and the production of anti-inflammatory compounds, and it has also been found to produce a range of enzymes, including amylases, lipases, and proteases, which enable it to degrade a variety of organic substrates.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyMicrococcaceae
GenusRothia
SpeciesRothia mucilaginosa
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Rothia mucilaginosa
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Rothia mucilaginosa strain UMB0024 .16933_8_62.9, whole genome

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1566 genes

Non-Coding Genes

213 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
short chain dehydrogenaseCYK05_04930Not AvailableNegative1208841 - 120958426312.4
beta-ketoacyl-acp reductaseCYK05_04935Not AvailableNegative1209658 - 121037425519.7
acetone carboxylaseCYK05_04940Not AvailablePositive1210661 - 12108888894.53
metal-dependent hydrolaseCYK05_04945Not AvailablePositive1211041 - 121176925150.1
abc transporter atp-binding proteinCYK05_04950Not AvailableNegative1212541 - 121413958229.7
biotin transporter bioyCYK05_04955Not AvailablePositive1214432 - 121507321834.1
abc transporter atp-binding proteinCYK05_04960Not AvailablePositive1215106 - 121599331786.9
abc transporter permeaseCYK05_04965Not AvailablePositive1215983 - 121665724587.8
duf4253 domain-containing proteinCYK05_04970Not AvailableNegative1216737 - 121759132437.5
phosphohydrolaseCYK05_04975Not AvailablePositive1218132 - 121863218713.4

Displaying genes 981 – 990 of 1779 in total

Metabolites

2 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0014342Methylimidazoleacetic acidC6H8N2O2Chemical structure of Methylimidazoleacetic acidNULL
Average140.1399Da
Monoisotopic140.05857751Da

Displaying 1–2 of 2 metabolites

Health Effects

Health ConditionRelationReference
Abdominal infectionsCausesPMC10417112
TonsillitisCausesPMC10417112
SpondylodiscitisCausesPMC10417112
KeratitisCausesPMC10417112
MeningitisCausesPMC10417112
OsteomyelitisCausesPMC10417112
BronchitisCausesPMC10417112
PneumoniaCausesPMC10417112
EndocarditisCausesPMC10417112
SepticemiaCausesPMC10417112

Displaying health effects 1 – 10 of 11 in total