Rothia mucilaginosa

Gram-positiveCocciMotileMicroaerophile

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Micrococcaceae

Genus

Rothia

Description

Rothia mucilaginosa is a gram-positive, coccoid-shaped microbe that thrives in mesophilic temperatures, classified as a chemoheterotroph, and can be found in various body sites, including the skin, respiratory tract, and gastrointestinal tract, of humans and other species. As a chemoheterotroph, R. mucilaginosa relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its growth. Its gram-positive cell wall and coccoid shape allow it to maintain its structure and withstand environmental stresses. The microbe's mesophilic temperature preference enables it to adapt to a wide range of environments, from the human body to various ecological niches. As a facultative anaerobe, R. mucilaginosa can survive in both oxygen-rich and oxygen-poor conditions, making it a versatile microorganism. Its ability to colonize different body sites in various species highlights its adaptability and capacity to coexist with diverse host organisms. Notably, R. mucilaginosa has been implicated in oral and respiratory infections, and its role in the human microbiome is still being explored, with recent studies suggesting that it may play a role in the breakdown of complex sugars and the production of anti-inflammatory compounds, and it has also been found to produce a range of enzymes, including amylases, lipases, and proteases, which enable it to degrade a variety of organic substrates.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyMicrococcaceae
GenusRothia
SpeciesRothia mucilaginosa
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Rothia mucilaginosa
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Rothia mucilaginosa strain UMB0024 .16933_8_62.9, whole genome

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1566 genes

Non-Coding Genes

213 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptidaseCYK05_00140Not AvailableNegative40051 - 4177560234.3
lipoate-protein ligase bCYK05_00145Not AvailablePositive41996 - 4267324884.8
lipoyl synthaseCYK05_00150Not AvailablePositive42838 - 4384537376.9
duf4191 domain-containing proteinCYK05_00155Not AvailablePositive44055 - 4477126193.4
type i glutamate--ammonia ligaseCYK05_00160Not AvailablePositive45118 - 4654252885.2
acetolactate decarboxylaseCYK05_00165Not AvailablePositive47226 - 4797527783.2
hit family proteinCYK05_00170Not AvailableNegative48102 - 4853015678.7
mbl fold metallo-hydrolaseCYK05_00175Not AvailableNegative48584 - 4926124218.0
transcriptional repressorCYK05_00180Not AvailablePositive49418 - 4988217311.6
metal abc transporter permeaseCYK05_00185Not AvailableNegative50147 - 5106731850.2

Displaying genes 31 – 40 of 1779 in total

Metabolites

4 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0014342Methylimidazoleacetic acidC6H8N2O2Chemical structure of Methylimidazoleacetic acidNULL
Average140.1399Da
Monoisotopic140.05857751Da
BASm0039676Clostridium nexileNot availableNot availableNot available
BASm0039735Streptococcus anginosusNot availableNot availableNot available

Displaying 1–4 of 4 metabolites

Health Effects

Health ConditionRelationReference
Abdominal infectionsCausesPMC10417112
TonsillitisCausesPMC10417112
SpondylodiscitisCausesPMC10417112
KeratitisCausesPMC10417112
MeningitisCausesPMC10417112
OsteomyelitisCausesPMC10417112
BronchitisCausesPMC10417112
PneumoniaCausesPMC10417112
EndocarditisCausesPMC10417112
SepticemiaCausesPMC10417112

Displaying health effects 1 – 10 of 11 in total