Streptomyces avermitilis

Gram-positiveTailedMotileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces avermitilis is a gram-positive, filamentous bacterium characterized by its rod shape, mesophilic temperature preference, heterotrophic metabolism, and obligate aerobic nature. As a member of the Streptomyces genus, it exhibits a complex life cycle and forms branched filaments resembling fungal hyphae, which further distinguishes it from other bacterial species. The gram-positive nature of S. avermitilis is indicative of its thick peptidoglycan cell wall, which is vital for its structural integrity and resilience in various environments. Being mesophilic, S. avermitilis thrives optimally at moderate temperatures, typically between 25°C and 37°C, making it well-suited for life in soil and decaying organic matter. As a heterotroph, it derives energy and carbon from organic compounds, efficiently breaking down complex substrates and playing a crucial role in the carbon cycle. Its obligate aerobic classification necessitates the presence of oxygen for respiration, which is essential for its metabolic processes and energy production. S. avermitilis is noteworthy for its ability to produce a variety of bioactive compounds, most famously avermectins, which are used as antiparasitic agents in veterinary medicine and agriculture. The discovery of these compounds has revolutionized parasite control in both livestock and crops, leading to significant economic benefits. Additionally, this bacterium has a rich history in the field of biotechnology, as it has been studied extensively for its potential in natural product discovery, contributing to our understanding of microbial ecology and the development of new therapeutic agents. Its ability to decompose complex organic materials also highlights its ecological importance in nutrient recycling and soil health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces avermitilis
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeTailed
MobilityYes
Flagellar presenceYes
Number of membranes1
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature25
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationSporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces avermitilis

Accession NumberBJHX00000000.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

9908 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
udp-glucose 4-epimeraseSAV14893_000010Not Available+1093 - 205833301.0
ndp-hexose 2,3-dehydrataseSAV14893_000020Not Available-2851 - 424551720.6
hypothetical proteinSAV14893_000030Not Available-4258 - 485722368.6
hypothetical proteinSAV14893_000040Not Available-4748 - 616051120.9
thioesteraseSAV14893_000050Not Available+6398 - 715027331.3
fmn-binding glutamate synthase family proteinSAV14893_000060Not Available+7502 - 908557270.6
pyruvate dehydrogenaseSAV14893_000070Not Available+9099 - 1086262377.4
hypothetical proteinSAV14893_000080Not Available-11085 - 1228442899.2
hypothetical proteinSAV14893_000090Not Available+12465 - 126385950.14
hypothetical proteinSAV14893_000100Not Available-12628 - 1296311826.8

Displaying genes 1 – 10 of 9908 in total

Pathways

3 pathways

Metabolites

19 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001885Tetra-mu3-sulfido-tetrairon(1+)Fe4S4Chemical structure of Tetra-mu3-sulfido-tetrairon(1+)Not available
Average351.62Da
Monoisotopic351.62748Da
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da
BASm0014038Malic acidC4H6O5Chemical structure of Malic acid97-67-6
Average134.0874Da
Monoisotopic134.021523302Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0017272LipoamideC8H15NOS2Chemical structure of Lipoamide940-69-2
Average205.341Da
Monoisotopic205.059505487Da
BASm0017274DihydrolipoamideC8H17NOS2Chemical structure of Dihydrolipoamide3884-47-7
Average207.357Da
Monoisotopic207.075155551Da
BASm0017278Methacrylyl-CoAC25H40N7O17P3SChemical structure of Methacrylyl-CoA6008-91-9
Average835.608Da
Monoisotopic835.141423115Da

Displaying 1–10 of 19 metabolites