Streptomyces antibioticus

Gram-positive

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Kitasatosporales

Family

Streptomycetaceae

Genus

Streptomyces

Description

Streptomyces antibioticus is a Gram-positive bacterium notable for its ability to produce a variety of bioactive compounds, including the antibiotic streptomycin. This filamentous microbe belongs to the genus Streptomyces, which is well-known for its role in natural antibiotic production and soil ecology. Characteristically, S. antibioticus exhibits a complex life cycle that includes the formation of mycelium and spores, contributing to its resilience in various environments. The Gram-positive nature of S. antibioticus is indicative of its thick peptidoglycan layer, which is a common feature among members of this genus and plays a critical role in maintaining cell integrity. This structural characteristic is essential for its survival in competitive microbial communities, particularly in soil environments where it can engage in interactions with other microorganisms. S. antibioticus is primarily recognized for its production of streptomycin, an aminoglycoside antibiotic that has been instrumental in the treatment of bacterial infections, particularly those caused by Mycobacterium tuberculosis. The ability of this bacterium to synthesize such potent compounds highlights its ecological significance, as it may contribute to the regulation of microbial populations in its natural habitat. In summary, Streptomyces antibioticus exemplifies the intricate relationships between microbial physiology, antibiotic production, and ecological interactions, underscoring the importance of soil-dwelling actinomycetes in both health and disease management.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderKitasatosporales
FamilyStreptomycetaceae
GenusStreptomyces
SpeciesStreptomyces antibioticus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptomyces antibioticus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptomyces antibioticus strain NRRL B-2032 P097contig99.1, whole

Gene Summary

Adenine Count

1401744 bp

Thymine Count

1401959 bp

Guanine Count

3567324 bp

Cytosine Count

3607817 bp

Genome Length

9978861 bp

Protein-coding Genes

8407 genes

Non-Coding Genes

85 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ketol-acid reductoisomeraseADK77_00005Q9FBT8Positive1 - 80329246.8
Ncrna_class:otherNot AvailableNot AvailablePositive170 - 244Not Available
5s ribosomal rnaNot AvailableNot AvailablePositive210 - 326Not Available
16s ribosomal rnaNot AvailableNot AvailablePositive618 - 2149Not Available
Ncrna_class:otherNot AvailableNot AvailablePositive1006 - 1080Not Available
peroxidaseADK77_00010Q743F4Negative1102 - 209435897.3
hypothetical proteinADK77_00015Not AvailableNegative2133 - 295730716.2
Ncrna_class:otherNot AvailableNot AvailablePositive3475 - 3549Not Available
glyoxalaseADK77_00025Not AvailableNegative3911 - 436615968.9
Ncrna_class:otherNot AvailableNot AvailablePositive4912 - 4980Not Available

Displaying genes 1 – 10 of 677 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

62 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm00004323,5-dichlorocatecholC6H4Cl2O2Chemical structure of 3,5-dichlorocatecholNot available
Average179.001Da
Monoisotopic177.9588348Da
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm00014072,5-dichlorohydroquinoneC6H4Cl2O2Chemical structure of 2,5-dichlorohydroquinoneNot available
Average179Da
Monoisotopic177.9588348Da
BASm00015513D-3,5/4-trihydroxycyclohexane-1,2-dioneC6H8O5Chemical structure of 3D-3,5/4-trihydroxycyclohexane-1,2-dioneNot available
Average160.125Da
Monoisotopic160.0371734Da
BASm00016432,5-dichlorocyclohexa-2,5-dien-1,4-diolC6H6Cl2O2Chemical structure of 2,5-dichlorocyclohexa-2,5-dien-1,4-diolNot available
Average181.01Da
Monoisotopic179.9744848Da

Displaying 1–10 of 62 metabolites

Health Effects

No health effects information available for this bacterium.