Bifidobacterium bifidum str. TMC 3115

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium bifidum strain TMC 3115 is a Gram-positive, nonsporulating rod-shaped bacterium that thrives in anaerobic environments, typically associated with the gastrointestinal tracts of various hosts. This species is part of the Bifidobacteriaceae family and is known for its role as a beneficial microbe within the gut microbiome, contributing to the maintenance of gut health and the modulation of the immune system. B. bifidum str. TMC 3115 is adapted to its host-associated habitat, where it engages in fermentative metabolism, utilizing carbohydrates to produce short-chain fatty acids that are pivotal for colonic health. Its anaerobic requirement indicates a preference for environments devoid of oxygen, which aligns with the conditions found in the intestines of mammals. The presence of B. bifidum in the gut microbiota is associated with various beneficial effects, including the enhancement of nutrient absorption and the inhibition of pathogenic microbes, although the precise mechanisms of action and the full spectrum of its interactions within the microbiome remain areas of ongoing research. Understanding the specialized adaptations of B. bifidum str. TMC 3115 enhances our knowledge of gut microbiota composition and its implications for host health, particularly in the context of probiotic applications and gut microbiome modulation.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium bifidum
StrainTMC 3115

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium bifidum str. TMC 3115
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium bifidum strain TMC 3115 chromosome, complete

Gene Summary

Adenine Count

407115 bp

Thymine Count

403700 bp

Guanine Count

684818 bp

Cytosine Count

683261 bp

Genome Length

2178894 bp

Protein-coding Genes

1759 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fkbp-type peptidyl-prolyl cis-trans isomeraseBBTM_RS00395Not AvailablePositive95771 - 9617514051.7
primosomal protein n'BBTM_RS00400Not AvailablePositive96234 - 9671217369.6
paqr family membrane homeostasis protein trhaBBTM_RS00405Not AvailableNegative97595 - 9848232103.9
sensor histidine kinaseBBTM_RS00410Not AvailablePositive98619 - 10010654786.6
whib family transcriptional regulatorBBTM_RS00415Not AvailableNegative100241 - 10051910374.4
ftsk/spoiiie domain-containing proteinBBTM_RS00420Not AvailableNegative100635 - 10255468850.0
lcp family proteinBBTM_RS00425Not AvailableNegative102713 - 10418851570.9
whib family transcriptional regulatorBBTM_RS00430Not AvailablePositive104470 - 10476911604.4
glycosyltransferase family 2 proteinBBTM_RS00435Not AvailablePositive104803 - 107952112034.0
duf5719 family proteinBBTM_RS00440Not AvailablePositive107949 - 10946051074.6

Displaying genes 81 – 90 of 1823 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GhCausesPMC10522390

Displaying health effects 1 – 1 of 1 in total