Bifidobacterium bifidum str. TMC 3115

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium bifidum strain TMC 3115 is a Gram-positive, nonsporulating rod-shaped bacterium that thrives in anaerobic environments, typically associated with the gastrointestinal tracts of various hosts. This species is part of the Bifidobacteriaceae family and is known for its role as a beneficial microbe within the gut microbiome, contributing to the maintenance of gut health and the modulation of the immune system. B. bifidum str. TMC 3115 is adapted to its host-associated habitat, where it engages in fermentative metabolism, utilizing carbohydrates to produce short-chain fatty acids that are pivotal for colonic health. Its anaerobic requirement indicates a preference for environments devoid of oxygen, which aligns with the conditions found in the intestines of mammals. The presence of B. bifidum in the gut microbiota is associated with various beneficial effects, including the enhancement of nutrient absorption and the inhibition of pathogenic microbes, although the precise mechanisms of action and the full spectrum of its interactions within the microbiome remain areas of ongoing research. Understanding the specialized adaptations of B. bifidum str. TMC 3115 enhances our knowledge of gut microbiota composition and its implications for host health, particularly in the context of probiotic applications and gut microbiome modulation.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium bifidum
StrainTMC 3115

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium bifidum str. TMC 3115
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Rodentia
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium bifidum strain TMC 3115 chromosome, complete

Gene Summary

Adenine Count

407115 bp

Thymine Count

403700 bp

Guanine Count

684818 bp

Cytosine Count

683261 bp

Genome Length

2178894 bp

Protein-coding Genes

1759 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
guab3 family imp dehydrogenase-related proteinBBTM_RS01845Not AvailableNegative423372 - 42449339701.4
nadp-dependent isocitrate dehydrogenaseBBTM_RS01850Not AvailablePositive424653 - 42587345279.7
xylose abc transporterBBTM_RS01855Not AvailablePositive426056 - 42765455879.9
amp-dependent synthetase/ligaseBBTM_RS01860Not AvailableNegative427801 - 42961565784.6
m23 family metallopeptidaseBBTM_RS09450Not AvailableNegative429726 - 43013014128.6
hypothetical proteinBBTM_RS09455Not AvailableNegative430405 - 43068310153.8
Trna-asnNot AvailableNot AvailablePositive430802 - 430877Not Available
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex transferase subunit tsadBBTM_RS01875Not AvailableNegative431303 - 43234635998.2
ribosomal protein s18-alanine n-acetyltransferaseBBTM_RS01880Not AvailableNegative432343 - 43292421418.3
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex dimerization subunit type 1 tsabBBTM_RS01885Not AvailableNegative432924 - 43379030395.0

Displaying genes 371 – 380 of 1823 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GhCausesPMC10522390

Displaying health effects 1 – 1 of 1 in total